DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG13252 and TECTA

DIOPT Version :9

Sequence 1:NP_649248.3 Gene:CG13252 / 40289 FlyBaseID:FBgn0037016 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_005413.2 Gene:TECTA / 7007 HGNCID:11720 Length:2155 Species:Homo sapiens


Alignment Length:298 Identity:62/298 - (20%)
Similarity:91/298 - (30%) Gaps:109/298 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 FVSSATTL----DQEPLPDLCQSVKCPPDAEMQCPADSSIRHNLLAVDLIKS------------- 69
            :::|...|    ::.||.|..:     ||..   ||.|       .:||.:|             
Human   453 YINSTCGLCGNYNKNPLDDFLR-----PDGR---PAMS-------VLDLGESWRVYHADWKCDSG 502

  Fly    70 ---NAVELPNASE----------MASAADGVSYNRGLISDED-YVQCCLNRKC------------ 108
               |..:...|:|          ..:..||..:..|.:.|.. :|..|:...|            
Human   503 CVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQA 567

  Fly   109 ------VCKTCYIP--------------DCPSDADEDVVVVELVPENNQTPGECCGTYECQAEPN 153
                  ||:...||              .|||.:...|.       .:..|..|.   :..|..|
Human   568 IQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVC-------TSSCPDTCS---DLTASRN 622

  Fly   154 CTVVRDTDFHWLKQCRR-CKCESGLKICHKTCDERAEGVCQSKISGMFYKDGE-NW-TENCKT-C 214
            |..          .|.. |:|..|..:....|....:  |.....|.:|..|| .| |.||.. |
Human   623 CAT----------PCTEGCECNQGFVLSTSQCVPLHK--CGCDFDGHYYTMGEFFWATANCTVQC 675

  Fly   215 ECEKGEPKCTMSFCGNLNCPSEQQVMLKDTCCPVCWPK 252
            .||:|..    .:|.|..|.|.:...::|. ...|:||
Human   676 LCEEGGD----VYCFNKTCGSGEVCAVEDG-YQGCFPK 708

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13252NP_649248.3 VWC 197..249 CDD:302663 17/54 (31%)
TECTANP_005413.2 NIDO 98..254 CDD:214712
VWD 322..478 CDD:278521 7/29 (24%)
C8 517..591 CDD:214843 11/73 (15%)
TIL 597..650 CDD:280072 14/74 (19%)
VWC 652..706 CDD:302663 17/58 (29%)
VWD 703..865 CDD:214566 3/6 (50%)
C8 905..981 CDD:214843
TIL 984..1036 CDD:280072
VWD 1100..1258 CDD:278521
C8 1298..1368 CDD:285899
TIL 1372..1425 CDD:280072
VWD 1487..1639 CDD:278521
C8 1684..1757 CDD:214843
ZP 1805..2057 CDD:214579
Zona_pellucida 1937..2057 CDD:278526
FXa_inhibition 2089..2121 CDD:291342
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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