Protein Alignment CG13252 and MUC6

DIOPT Version :9

• Sequence 1: NP_649248.3
• Gene: CG13252 / 40289
• FlyBaseID: FBgn0037016
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_005952.2
• Gene: MUC6 / 4588
• HGNCID: 7517
• Length: 2439
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 87/429 - (20%)
• Similarity: 135/429 - (31%)
• Gaps: 174/429 - (40%)

  Fly    19 VLIFVSSATTLDQEPLPDLCQSVKCPPDAEMQCPADSSIRHNLLAVDLIKSNAVELPNASEMASA 83
            :||.::.|:   |:||..||.:.    :..|:...::..|:       :.|:.:||.|:.:.:..
Human   986 ILIRIARAS---QDPLCGLCGNF----NGNMKDDFETRSRY-------VASSELELVNSWKESPL 1036

  Fly    84 ADGVSYNRGLISDEDYVQCCLN--------RKCVCKTCYIPDCPSDADEDVVVVELVPENNQTPG 140
            ...||:    ::|    .|.||        |||                .|:       |:||..
Human  1037 CGDVSF----VTD----PCSLNAFRRSWAERKC----------------SVI-------NSQTFA 1070

  Fly   141 EC-CGTYECQAEPNCTVVRDTDFHWLKQCRRCKCESGLKICHKTCDERA--------EGVCQS-- 194
            .| ...|.......|  |||.          |.|:|| ..|...||..|        :|||..
Human  1071 TCHSKVYHLPYYEAC--VRDA----------CGCDSG-GDCECLCDAVAAYAQACLDKGVCVDWR 1122

  Fly   195 -----KISGMFY----KDGE---------NWTENCKTCEC---EKGEPKCTMSFCGNLNCPSEQQ 238
                 .|...||    :||.         |.|.:.:.|.|   .:..|...:..|  .||..::.
Human  1123 TPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGC--YNCSQDEY 1185

  Fly   239 VMLKDTCCPVCWPKCAPMP---HEKQDDGSYEDYV--------------------DESETPEEDS 280
            ...::..|..|.|...|.|   .:....||....|                    ..:.||...:
Human  1186 FDHEEGVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPT 1250

  Fly   281 LPPLLPDPL---------------------------------------------TTQQSAELVAT 300
            ..||||..|                                             ||:.:|...:.
Human  1251 QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASP 1315

  Fly   301 STTTSSNGTTSTTV-VPLAATVNCNNAFDQPKVVEVVNQ 338
            :||:::..||.||: :|..||...:     |.:.:..||
Human  1316 ATTSTAQSTTRTTMTLPTPATSGTS-----PTLPKSTNQ 1349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	13/67 (19%)
MUC6	NP_005952.2	VWD	40..192	CDD:214566
		C8	228..297	CDD:285899
		TIL	302..357	CDD:280072
		VWC_out	359..>403	CDD:214565
		VWD	386..549	CDD:214566
		C8	588..660	CDD:285899
		TIL	664..721	CDD:280072
		TIL	782..827	CDD:280072
		VWC	829..886	CDD:302663
		VWD	868..1017	CDD:278521	9/37 (24%)
		C8	1057..1127	CDD:285899	24/105 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1202..1455		27/153 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1471..1626
		1, truncated	1561..1738
		Approximate repeats	1607..1953
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1642..1834
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1868..1983
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2033..2077
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2090..2196
		PHA03255	2188..>2343	CDD:165513
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2233..2278
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2323..2348
		CT	2351..2434	CDD:214482

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900