DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13252 and Kcp

DIOPT Version :9

Sequence 1:	NP_649248.3	Gene:	CG13252 / 40289	FlyBaseID:	FBgn0037016	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_011239372.1	Gene:	Kcp / 333088	MGIID:	2141640	Length:	2120	Species:	Mus musculus

Alignment Length:	328	Identity:	85/328 - (25%)
Similarity:	109/328 - (33%)	Gaps:	127/328 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PYSHTPRR---------CLHQMLIIYVLIFVSSATTLDQEPLPD------LC--QSVKCPPD--A 47
            |.:| |||         ||:|     ...|.|.    ::.|.|:      ||  .||||.|.  |
Mouse   740 PCAH-PRRDACCPSCDGCLYQ-----GKEFASG----ERFPSPNVACHVCLCWEGSVKCEPRTCA 794

  Fly    48 EMQCPADSSIRHNLLAVDLIKSNAVELPNASEMASAAD-----GVSYNRGLISDE--DYVQCCLN 105
            ..|||                     .|...:...|.|     ||||   |.|.|  |..:.|
Mouse   795 PAQCP---------------------FPTREDCCPACDSCDYLGVSY---LSSQEFPDPREAC-- 833

  Fly   106 RKCVC----KTCYIPDCPSDADEDVVVVELVPENNQTPGECCGTYECQA---------------- 150
            ..|.|    .||....|...|....::|         |..||.|  ||.
Mouse   834 NLCTCLGGFVTCTRRPCEPPACSHPLIV---------PEHCCPT--CQGCLYHGITAALGETLPD 887

  Fly   151 --EPNCTVVRDTDFHWLKQCRRCKCESGLKICHK------TCDERAEG-----VCQSKIS-GMFY 201
              :|.|::              |.||.|...|.|      .|...:.|     ||:|.:| |..:
Mouse   888 PLDPTCSL--------------CTCEEGSMRCQKKPCPPAPCAHPSPGPCFCPVCRSCLSQGREH 938

  Fly   202 KDGENW---TENCKTCECEKGEPKCTMSFCGNLNCPSEQQVMLKDTCCPVCWPKCAPMPHEKQDD 263
            :|||.:   ..:|:.|.|..|:..||...|.:|.|  ..||....||||.| ..|.....|..:.
Mouse   939 QDGEEFEGPEGSCERCRCLAGQVSCTRLQCPSLPC--LHQVTEPGTCCPRC-TGCLARGEEHPEG 1000

  Fly   264 GSY 266
            .|:
Mouse  1001 SSW 1003

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	20/55 (36%)
Kcp	XP_011239372.1	VWC	166..220	CDD:278520
		VWC	224..280	CDD:327433
		VWC	285..341	CDD:327433
		VWC	344..399	CDD:327433
		VWC	458..514	CDD:278520
		VWC	517..573	CDD:327433
		VWC	634..690	CDD:327433
		VWC	<717..753	CDD:327433	5/13 (38%)
		VWC	931..987	CDD:327433	20/57 (35%)
		VWC	<1173..1214	CDD:214564
		VWC	1221..1278	CDD:214564
		VWD	1285..1432	CDD:365869
		C8	1482..1549	CDD:370094
		Glutenin_hmw	<1757..>1975	CDD:367362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900