DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13252 and Crim1

DIOPT Version :9

Sequence 1:	NP_649248.3	Gene:	CG13252 / 40289	FlyBaseID:	FBgn0037016	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001162574.1	Gene:	Crim1 / 298744	RGDID:	1308710	Length:	1037	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	82/321 - (25%)
Similarity:	121/321 - (37%)	Gaps:	97/321 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PRRCLHQMLII-YVLIFVSSAT--------TLDQEPLPDL-CQSVKCPPDAEMQCPADSSIRHNL 61
            |..||.::... |:.|.||.|:        ..:.:|:..: |.:|:|||..:..||.||
  Rat   214 PAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDS------ 272

  Fly    62 LAVDLIKSNAVELPNASEMASAADGVSYNRGLISDEDYVQCC-LNRKCVCKT--CYIPDCPSDAD 123
                          ..:::...|||               || |..:|.|.:  |..|.|
  Rat   273 --------------YETQVRLTADG---------------CCTLPARCECLSGLCAFPVC----- 303

  Fly   124 EDVVVVELVPENNQTPGECCGTYEC--QAEPNCTV----VRDTDFHWLKQCRRCKCESGLKICHK 182
            |......:|...:.|||:||..:||  :.:|.|..    ..|.|...:..||.|:|:.|:.||..
  Rat   304 EVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFT 368

  Fly   183 T-CDER-------AEG----VCQSKI-----------SGMFYKDGENWTE-NCKTCECEKGEPKC 223
            . |.|.       .||    ||:..|           :|.....|:.|.| :|..|:|..|||.|
  Rat   369 AQCGELNCERYYVPEGECCPVCEDPIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHC 433

  Fly   224 TMSFCGNLNCPSEQQVMLKDTCCPVCW---------PKCAPMPH--EKQDDGSYEDYVDES 273
            ..:.||. :|  ...|.:...|||||.         |.|..:.:  .|:.|..|...:|.:
  Rat   434 VATACGQ-SC--MHPVKVPGECCPVCEEPTYITIDPPACGELSNCTLKEKDCVYGFKLDHN 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	18/52 (35%)
Crim1	NP_001162574.1	IB	37..>95	CDD:197525
		VWC	336..390	CDD:214564	14/53 (26%)
		VWC	403..456	CDD:214564	18/55 (33%)
		Antistasin	567..592	CDD:280912
		VWC	612..662	CDD:302663
		VWC	683..734	CDD:302663
		VWC	758..808	CDD:302663
		VWC	819..873	CDD:302663
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810