DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13252 and Otog

DIOPT Version :9

Sequence 1:	NP_649248.3	Gene:	CG13252 / 40289	FlyBaseID:	FBgn0037016	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001099732.1	Gene:	Otog / 292918	RGDID:	1306610	Length:	2902	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	93/407 - (22%)
Similarity:	132/407 - (32%)	Gaps:	162/407 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EPLPDLCQ-SVKCPPDAEMQCP--------ADSSI---RHNLLAVDLIK---SNAVELPNASEMA 81
            || |:.|| .|..|.|.| ||.        ::.:|   ||:.|.:...|   :::..:|.|.
  Rat  2364 EP-PETCQDGVLGPLDPE-QCQVLGEGCVCSEGTILHRRHSALCIPEDKCACTDSTGVPRAL--- 2423

  Fly    82 SAADGVSYNRGLISDEDYVQCCLNRKCVCK---TCYIPDCPSDADE------DVVVVELVPEN-- 135
                |.::|..|..      || .::|...   |...||||....|      :|::::...:.
  Rat  2424 ----GETWNSSLSG------CC-QQQCQAPDTITPMDPDCPGPRPESCPRFGEVILLQPTEDPCC 2477

  Fly   136 -------NQT----------PG----------ECCGTYECQAEPN-CTVVRDTDFHWLKQCRR-- 170
                   |||          ||          .||.:|.|:.:|. |      :...:..||:
  Rat  2478 LGSVCVCNQTLCEGLAPTCRPGHRLIPHFQEDSCCPSYSCECDPGLC------EAEQVPTCRQDQ 2536

  Fly   171 ----------CKCESGLKICHKTCDERAEGVCQSKISGMFYKDGE------NWTENC---KTCEC 216
                      | |.|....|.:..|...|  ||         :||      |.||.|   ..|.|
  Rat  2537 VLIEGRLGDSC-CPSYFCGCGECPDAMPE--CQ---------EGEVLTVHRNSTELCCPLYQCVC 2589

  Fly   217 EKGEPKCTMSF-CGNLNC---PSEQQVMLKDTCCPV--CWPKCAPMP----HEKQDDGSYEDYVD 271
            |        || |..:.|   .|..:|...|.|||.  |...|..:|    |..:.....|:::.
  Rat  2590 E--------SFRCPQIQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMH 2646

  Fly   272 ESETP------EEDSLPPLLPDPLTTQQSAELVATSTTTSSNGTTSTTVVPLAA-----TVNCNN 325
            ..|..      |....|..|...|...|..:                |||.|:|     |..|.:
  Rat  2647 SVENVCGCAKYECVKAPVCLSRELGVMQPGQ----------------TVVELSADGVCHTSRCTD 2695

  Fly   326 AFDQPKVVEVVNQTNYY 342
            ..|.        .||:|
  Rat  2696 VLDP--------LTNFY 2704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	19/66 (29%)
Otog	NP_001099732.1	VWD	143..293	CDD:278521
		C8	339..403	CDD:285899
		TIL	417..465	CDD:280072
		VWC	467..>502	CDD:302663
		VWD	505..660	CDD:278521
		C8	700..761	CDD:285899
		TIL	771..835	CDD:280072
		TIL	875..937	CDD:280072
		VWD	968..1122	CDD:214566
		C8	1157..1231	CDD:214843
		Fascin	<1296..1387	CDD:304938
		VWD	2089..2243	CDD:278521
		C8	2279..2347	CDD:214843
		TIL	2350..2411	CDD:280072	15/48 (31%)
		CT	2819..2901	CDD:214482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900