DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13252 and Vwf

DIOPT Version :9

Sequence 1:NP_649248.3 Gene:CG13252 / 40289 FlyBaseID:FBgn0037016 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_035838.3 Gene:Vwf / 22371 MGIID:98941 Length:2813 Species:Mus musculus


Alignment Length:312 Identity:69/312 - (22%)
Similarity:93/312 - (29%) Gaps:90/312 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 CPPDAEMQCPADSSIRHNLLAVDLIKSNAVELPNASEMASAADGVSYNRGLISDEDYVQC----- 102
            |.|:.|..|             ||...|   ||..............|.|        :|     
Mouse  2319 CCPEYECVC-------------DLFNCN---LPPVPPCEGGLQPTLTNPG--------ECRPTFT 2359

  Fly   103 CLNRKCVCKTCYIPDCPSDADEDVVVVELVPENNQTP----GECCGTYECQAEPNCTVVRDT--- 160
            |..||..||....|.||.               ::||    .:||..|||.    |:.|..|   
Mouse  2360 CACRKEECKRVSPPSCPP---------------HRTPTLRKTQCCDEYECA----CSCVNSTLSC 2405

  Fly   161 DFHWLKQC--RRCKCESGLKICHKTCDERAEGVCQSKISGMFYKDGENWTENCKTCECEKGEP-- 221
            ...:|...  ..|.|.:...:..|.|..|          |..|..|:.|.|.|.||.|...|.  
Mouse  2406 PLGYLASATTNDCGCTTTTCLPDKVCVHR----------GTVYPVGQFWEEGCDTCTCTDMEDTV 2460

  Fly   222 ------KCTMSFCGNLNCPSEQQVMLKDTCCPVCWPK-CAPMPHEKQDD--GSYEDYVDESETPE 277
                  :|:...|.:...|....|:.:..||..|.|. |..:....:.|  .|::........||
Mouse  2461 VGLRVVQCSQRPCEDSCQPGFSYVLHEGECCGRCLPSACKVVAGSLRGDSHSSWKSVGSRWAVPE 2525

  Fly   278 EDSLPPLLPDPLTTQQSAELVATSTTTSSNGTTSTTVVPLAAT---VNCNNA 326
            .    |.|.:.....:.|..|     ...|.:.....||...|   :||..:
Mouse  2526 N----PCLVNECVRVEDAVFV-----QQRNISCPQLAVPTCPTGFQLNCETS 2568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13252NP_649248.3 VWC 197..249 CDD:302663 16/59 (27%)
VwfNP_035838.3 VWD 35..179 CDD:278521
C8 218..292 CDD:214843
TIL 295..348 CDD:280072
VWC 350..>394 CDD:302663
VWD 377..540 CDD:214566
C8 580..648 CDD:285899
TIL 652..707 CDD:280072
Amino-terminal 764..787
E1 788..833
CX 826..853
VWD 856..1011 CDD:214566
C8 1053..1127 CDD:214843
TIL 1146..1196 CDD:280072
VWA_N2 1198..1276 CDD:292782
VWA 1277..1449 CDD:214621
VWA 1498..1658 CDD:278519
VWA 1691..1860 CDD:278519
VWD 1950..2102 CDD:278521
C8 2136..2199 CDD:285899
TIL 2203..2254 CDD:280072
E2 2216..2261
VWC 2257..2321 CDD:214564 1/1 (100%)
VWC 2431..2494 CDD:214564 18/72 (25%)
Cell attachment site. /evidence=ECO:0000250 2507..2509 0/1 (0%)
VWC 2582..2644 CDD:302663
CT 2727..2808 CDD:214482
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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