DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cmpy and CCN6

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_003871.1	Gene:	CCN6 / 8838	HGNCID:	12771	Length:	354	Species:	Homo sapiens

Alignment Length:	229	Identity:	51/229 - (22%)
Similarity:	73/229 - (31%)	Gaps:	90/229 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 KCYCN-PKECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCG------------------GPG 133
            |.:|: |.:|.. :.|.||....::.|.|.||:||||..||.|.                  .|.
Human    45 KQFCHWPCKCPQ-QKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPR 108

  Fly   134 GFSGQC-----------------------EPPLQCVTKLPISSGLGVCMDL-------QHLTAL- 167
            ..:|.|                       .|...|   |.:|..:| |..|       .|.:..
Human   109 YETGVCAYLVAVGCEFNQVHYHNGQVFQPNPLFSC---LCVSGAIG-CTPLFIPKLAGSHCSGAK 169

  Fly   168 --TYSQHDNCSDSDSIVLEPGCE-----------------ITNKRCQC----W-PTMRTC---LS 205
              ..|...|||      |||..:                 |..|:|..    | |..|||   :|
Human   170 GGKKSDQSNCS------LEPLLQQLSTSYKTMPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGIS 228

  Fly   206 ELTSDGGSPDDSRWHFK--NLEDCQLNLQNLIKL 237
            ...::..|..:.|...:  .::.|..|:...||:
Human   229 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKI 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	21/95 (22%)
CCN6	NP_003871.1	IGFBP	48..100	CDD:365955	17/52 (33%)
CCN6	NP_003871.1	GHB_like	275..341	CDD:389804
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000