DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and Ccn1

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_112617.3	Gene:	Ccn1 / 83476	RGDID:	620763	Length:	379	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	38/148 - (25%)
Similarity:	58/148 - (39%)	Gaps:	41/148 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LNVSALLIYLWCYLLLVMAASGGSNHVVNGLKCYCNPKECDVIRSPDC-PGKGLMLWDPCKCCRI 120
            |.|:..|::|....|....|:           |:| |.|     :|.| ||.||:. |.|.||::
  Rat     9 LAVAVTLLHLTRLALSTCPAA-----------CHC-PLE-----APKCAPGVGLVR-DGCGCCKV 55

  Fly   121 CAKTLGESCGGPGGFSGQCE--PPLQCVTKLPISSGLGVCMDLQHLTALTYSQHDNCSDSDSIV- 182
            |||.|.|.|..    :..|:  ..|:|......::..|:|.        ..|:...|..:..|.
  Rat    56 CAKQLNEDCSK----TQPCDHTKGLECNFGASSTALKGICR--------AQSEGRPCEYNSRIYQ 108

  Fly   183 ----LEPGCEITNKRCQC 196
                .:|.|:   .:|.|
  Rat   109 NGESFQPNCK---HQCTC 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	21/56 (38%)
Ccn1	NP_112617.3	IGFBP	26..78	CDD:395164	23/73 (32%)
		VWC	100..159	CDD:214564	6/27 (22%)
		TSP1_CCN	227..270	CDD:408805
		Heparin-binding. /evidence=ECO:0000250\|UniProtKB:P18406	277..313
		Cys_knot	291..373	CDD:394966
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000