DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and ccn5

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_031749917.1	Gene:	ccn5 / 496678	XenbaseID:	XB-GENE-876336	Length:	314	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	56/208 - (26%)
Similarity:	82/208 - (39%)	Gaps:	57/208 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VVLEQDVRT-RSSQGERKRGLAGKQQHNNAKLPLRMRS----NGSYF----GRLNVSALLIYLWC 68
            |:|.:.:.| ....|.||    ||..|    :|...:|    ||:..    |.|| ..||:..:|
Frog    27 VLLPESINTVLDGAGSRK----GKPHH----IPNSRQSAGLMNGACMAMDPGILN-RYLLLLGYC 82

  Fly    69 YLLLVMAASGGSNHVVNGLKCYCN--PKECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCGG 131
            .|..:.|.       :....|:|:  |        |.||....::.|.|.||||||:.|||||
Frog    83 ILPQICAQ-------LCRTPCFCSWIP--------PRCPPGVPVIVDGCGCCRICARQLGESC-- 130

  Fly   132 PGGFSGQCEPPLQCVTKLPI-SSGLGVCMDLQHLTALTYS-----QHDNCSDSDSIVLEPGCEIT 190
              .....|:...:.:...|. |:|.|.|         .|:     ::|.....|..|.:|.|:.
Frog   131 --DHLYLCDESKELLCDYPTGSNGRGTC---------NYNYDGSCEYDGKEYKDGEVFQPNCKF- 183

  Fly   191 NKRCQCWPTMRTC 203
              :|:|.....||
Frog   184 --QCKCIDGGITC 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	19/55 (35%)
ccn5	XP_031749917.1	IGFBP	88..138	CDD:395164	21/68 (31%)
		VWC	164..223	CDD:214564	9/34 (26%)
		TSP1_CCN	256..299	CDD:408805
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000