DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and CCN1

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001545.2	Gene:	CCN1 / 3491	HGNCID:	2654	Length:	381	Species:	Homo sapiens

Alignment Length:	116	Identity:	32/116 - (27%)
Similarity:	48/116 - (41%)	Gaps:	30/116 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 CYCNPKECDVIRSPDC-PGKGLMLWDPCKCCRICAKTLGESCGGPGGFSGQCE--PPLQCVTKLP 150
            |:| |.|     :|.| ||.||:. |.|.||::|||.|.|.|..    :..|:  ..|:|.....
Human    30 CHC-PLE-----APKCAPGVGLVR-DGCGCCKVCAKQLNEDCSK----TQPCDHTKGLECNFGAS 83

  Fly   151 ISSGLGVCMDLQHLTALTYSQHDNCSDSDSIV-----LEPGCEITNKRCQC 196
            .::..|:|.        ..|:...|..:..|.     .:|.|:   .:|.|
Human    84 STALKGICR--------AQSEGRPCEYNSRIYQNGESFQPNCK---HQCTC 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	21/56 (38%)
CCN1	NP_001545.2	IGFBP	26..78	CDD:365955	22/58 (38%)
		VWC	100..159	CDD:214564	6/27 (22%)
		TSP1	232..272	CDD:214559
		Heparin-binding. /evidence=ECO:0000250\|UniProtKB:P18406	279..315
		GHB_like	293..375	CDD:389804
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000