DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and Crim1

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001162574.1	Gene:	Crim1 / 298744	RGDID:	1308710	Length:	1037	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	66/225 - (29%)
Similarity:	94/225 - (41%)	Gaps:	76/225 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RGLAGKQQHNNAKLPLRMRSNGSYFGRLNVSALLIYLWCYLLLVMAASGGSNHVVNGLKCY-CNP 93
            |||||                   .|.|:||.|      .|||::|.||     ...|.|. |:.
  Rat     8 RGLAG-------------------CGHLSVSLL------GLLLLLARSG-----TRALVCLPCDE 42

  Fly    94 KECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCGGPGGFSGQCEPPLQCVTKLPISSG---- 154
            .:|:..||  |||.  ::...|.||.:||:...|||||..|..|.|:..|:||.:.|::..
  Rat    43 SKCEEPRS--CPGS--IVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITE 103

  Fly   155 --LGVCMDLQHLTALTYSQHDNCSDSDSIVLEP-------GCEITNKRCQCWPTMRTCLSELTSD 210
              :|||.|            ::..|...:..||       ||.|.|.||:| .|:|||
  Rat   104 YEVGVCED------------EDWDDDQLLGFEPCNENLISGCNIINGRCEC-STIRTC------- 148

  Fly   211 GGSPDDSRWHFKNLEDCQLNLQNLIKLEQE 240
                 ::.:.|...:.|   |..|.::|:|
  Rat   149 -----NNPFEFPRKDMC---LSALKRIEEE 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	21/53 (40%)
Crim1	NP_001162574.1	IB	37..>95	CDD:197525	24/61 (39%)
		VWC	336..390	CDD:214564
		VWC	403..456	CDD:214564
		Antistasin	567..592	CDD:280912
		VWC	612..662	CDD:302663
		VWC	683..734	CDD:302663
		VWC	758..808	CDD:302663
		VWC	819..873	CDD:302663
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910