DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and Ccn4

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_061353.1	Gene:	Ccn4 / 22402	MGIID:	1197008	Length:	367	Species:	Mus musculus

Alignment Length:	236	Identity:	48/236 - (20%)
Similarity:	74/236 - (31%)	Gaps:	104/236 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 YCN-PKECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCGGPGGFSGQCEP--PLQCVTKLPI 151
            :|. |.||.. ..|.||....::.|.|:||:|||:.||::|..    :..|:|  .|.|     .
Mouse    48 FCKWPCECPQ-SPPRCPLGVSLITDGCECCKICAQQLGDNCTE----AAICDPHRGLYC-----D 102

  Fly   152 SSG------LGVCMDLQH----LTALTYSQHD--------NCSDSDSIVLEPGC----------- 187
            .||      :|||..:..    |..:.|:..:        ||:..|..|   ||
Mouse   103 YSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTV---GCTPLCLSPRPPR 164

  Fly   188 ---------EITNKRCQCW-----------------------------------------PTMRT 202
                     .:..:.|:.|                                         |...|
Mouse   165 LWCRQPRHVRVPGQCCEQWVCDDDARRPRQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTT 229

  Fly   203 C-------LSELTSDGGSPDDSRWHFKNLEDCQLNLQNLIK 236
            |       :|.:.:......:||  ..||..|.:::|..||
Mouse   230 CGLGISTRISNVNARCWPEQESR--LCNLRPCDVDIQLHIK 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	20/56 (36%)
Ccn4	NP_061353.1	IGFBP	49..101	CDD:278641	20/56 (36%)
		VWC	123..181	CDD:214564	8/60 (13%)
		TSP_1	220..259	CDD:301595	8/40 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000