DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and Ccn1

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_034646.1	Gene:	Ccn1 / 16007	MGIID:	88613	Length:	379	Species:	Mus musculus

Alignment Length:	155	Identity:	40/155 - (25%)
Similarity:	61/155 - (39%)	Gaps:	41/155 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NGSYFGRLNVSALLIYLWCYLLLVMAASGGSNHVVNGLKCYCNPKECDVIRSPDC-PGKGLMLWD 113
            :.|.|..|.|:..|::|....|....|:           |:| |.|     :|.| ||.||:. |
Mouse     2 SSSTFRTLAVAVTLLHLTRLALSTCPAA-----------CHC-PLE-----APKCAPGVGLVR-D 48

  Fly   114 PCKCCRICAKTLGESCGGPGGFSGQCE--PPLQCVTKLPISSGLGVCMDLQHLTALTYSQHDNCS 176
            .|.||::|||.|.|.|..    :..|:  ..|:|......::..|:|.        ..|:...|.
Mouse    49 GCGCCKVCAKQLNEDCSK----TQPCDHTKGLECNFGASSTALKGICR--------AQSEGRPCE 101

  Fly   177 DSDSIV-----LEPGCEITNKRCQC 196
            .:..|.     .:|.|:   .:|.|
Mouse   102 YNSRIYQNGESFQPNCK---HQCTC 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	21/56 (38%)
Ccn1	NP_034646.1	IGFBP	26..78	CDD:365955	23/73 (32%)
		VWC	100..159	CDD:214564	6/27 (22%)
		TSP1	230..270	CDD:214559
		Heparin-binding. /evidence=ECO:0000269\|PubMed:10821835	277..313
		Cys_knot	291..373	CDD:333760
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000