Protein Alignment cmpy and CCN2

DIOPT Version :9

• Sequence 1: NP_001097652.1
• Gene: cmpy / 40288
• FlyBaseID: FBgn0037015
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_001892.2
• Gene: CCN2 / 1490
• HGNCID: 2500
• Length: 349
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 56/250 - (22%)
• Similarity: 80/250 - (32%)
• Gaps: 90/250 - (36%)

  Fly    86 GLKCYCNPKECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCGGPGGFSGQCEP--PLQCVTK 148
            |..| ..|..|....:|.||....::.|.|.|||:|||.|||.|..    ...|:|  .|.|...
Human    26 GQNC-SGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE----RDPCDPHKGLFCHFG 85

  Fly   149 LPISSGLGVCMDLQHLTAL----TYSQHDN----------CSDS----------DSIVLEPGC-- 187
            .|.:..:|||........:    .|...::          |.|.          |..:..|.|
Human    86 SPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPF 150

  Fly   188 ----EITNKRCQCW---------------------------PTM----------------RTC-- 203
                ::..|.|:.|                           |||                :||
Human   151 PRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGM 215

  Fly   204 --LSELTSDGGS---PDDSRWHFKNLEDCQLNLQNLIKLEQEFDEDYKIS-PSKF 252
              .:.:|:|..|   ...||  ...:..|:.:|:..||..::.....||| |.||
Human   216 GISTRVTNDNASCRLEKQSR--LCMVRPCEADLEENIKKGKKCIRTPKISKPIKF 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	20/55 (36%)
CCN2	NP_001892.2	IGFBP	29..82	CDD:395164	21/57 (37%)
		VWC	103..163	CDD:278520	8/59 (14%)
		TSP1_CCN	199..242	CDD:408805	7/44 (16%)
		Heparin-binding. /evidence=ECO:0000269|PubMed:12553878	247..349		7/21 (33%)
		GHB_like	253..345	CDD:419725	5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000