DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cmpy and ccn6

DIOPT Version :9

Sequence 1:	NP_001097652.1	Gene:	cmpy / 40288	FlyBaseID:	FBgn0037015	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_002936979.3	Gene:	ccn6 / 100488354	XenbaseID:	XB-GENE-967531	Length:	352	Species:	Xenopus tropicalis

Alignment Length:	199	Identity:	46/199 - (23%)
Similarity:	70/199 - (35%)	Gaps:	57/199 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 KCYCN-PKECDVIRSPDCPGKGLMLWDPCKCCRICAKTLGESCGGPGGFSGQCE----------- 140
            |.:|: |.:|.  ....||.....:.|.|.||:||||.|||||..    :..|:
Frog    45 KQFCHWPCKCS--HQSSCPPGMSRVKDGCGCCKICAKQLGESCNE----ADVCDHHRGLYCDYSA 103

  Fly   141 --PPLQCVTKLPISSGLGVCMDLQ----HLTALTYSQHDNCSDSDSIVLEPGCEITNKRCQCWPT 199
              |..:          :|:|..:.    .|..:.|........|...:    |...:....|.||
Frog   104 DRPKYE----------VGICKYMLAVGCELNGVLYKNGQTFQPSPHYL----CLCISDTIGCTPT 154

  Fly   200 M--RTCLSELTSDGGSPDDSRWHFKNLEDCQLNLQNLIKLEQEFDEDYKISPSKFTYKKLRR--K 260
            :  :...::..:..|.|..|     :..:|.|.       :..:..|||.:|   .||.|..  |
Frog   155 LVGKQDQNQCVTSPGQPKIS-----DNANCALE-------KDSYKPDYKFTP---VYKVLPLVWK 204

  Fly   261 RKSL 264
            ||.|
Frog   205 RKCL 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cmpy	NP_001097652.1	IGFBP	91..145	CDD:395164	20/67 (30%)
ccn6	XP_002936979.3	IGFBP	48..99	CDD:395164	19/56 (34%)
		TSP1_CCN	207..250	CDD:408805	1/2 (50%)
		GHB_like	273..340	CDD:419725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000