DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kni and RORA

DIOPT Version :9

Sequence 1:	NP_001287130.1	Gene:	kni / 40287	FlyBaseID:	FBgn0001320	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_599022.1	Gene:	RORA / 6095	HGNCID:	10258	Length:	556	Species:	Homo sapiens

Alignment Length:	138	Identity:	48/138 - (34%)
Similarity:	73/138 - (52%)	Gaps:	14/138 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNV 74
            ||:||:.::|.|:|..||||||.||.||..:.:|.| |..:..|:||:.:|..|:.|||:||..|
Human   106 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAV 169

  Fly    75 GMSKGGSRYGRRSN------WFKI--HCLLQEHEQAAAAAGKAPPLAG--GVSVGGAPSASSPVG 129
            |||:...::||.|.      :.::  |.:.|:........|:|.||..  .:|..|.......:.
Human   170 GMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLS 234

  Fly   130 S---PHTP 134
            :   .|||
Human   235 NYIDGHTP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kni	NP_001287130.1	NR_DBD_like	8..92	CDD:295381	37/87 (43%)
RORA	NP_599022.1	NR_DBD_ROR	99..193	CDD:143526	37/87 (43%)
RORA	NP_599022.1	NR_LBD_ROR_like	305..544	CDD:132737
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5442
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860