Protein Alignment kni and nr1d4a

DIOPT Version :10

• Sequence 1: NP_001287130.1
• Gene: kni / 40287
• FlyBaseID: FBgn0001320
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: XP_021325494.1
• Gene: nr1d4a / 563150
• ZFINID: ZDB-GENE-080403-5
• Length: 572
• Species: Danio rerio
• Alignment Length: 345
• Identity: 89/345 - (25%)
• Similarity: 127/345 - (36%)
• Gaps: 87/345 - (25%)

  Fly    10 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNV 74
            |||||:.|:|||:|...|||||.||.||.........|.....|:|.:.||..|:.||.:||.:|
Zfish   116 CKVCGDIASGFHYGVHACEGCKGFFRRSIQQNINYKMCVKNENCLIMRMNRNRCQHCRFKKCLSV 180

  Fly    75 GMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSAS-----SPVGSPHTP 134
            |||:...|:||.....| ..||.|.:....:..::       |:|...|..     ||:.:....
Zfish   181 GMSRDAVRFGRIPKREK-QRLLDEMQSYMNSLNES-------SMGMETSPQHEPPPSPIENQSKE 237

  Fly   135 GFGDMAAHLHHHHQQQQQQQVPRHPHMPLLGYPSYLSDPSAALPFFSMMGGVPHQSPFQLPPHLL 199
            ..|.::..........|.....|..:..:....||.:.|       |.....||.:|
Zfish   238 AIGALSRAYQDIFTNTQDHLNKRAGNNNISRSSSYQNSP-------SQDSNYPHANP-------- 287

  Fly   200 FPGYHASAAAAAASAADAAYRQEMYKHRQSVDSVESQ--------NRFSPA-------SQPPVVQ 249
            ..|||.:...:.:...           |..|.:.||:        ||:|.|       ||..|.|
Zfish   288 LAGYHTTTHESFSGPV-----------RCPVSTSESKCPVSLVDNNRYSYAPSFSQNHSQSSVNQ 341

  Fly   250 PTSSARQSPIDVCLEEDVHSVHSHQSSASLLHPIAIRATPTTPTSSSPLSFAAKMQSLSPVSVCS 314
            |:...:                :|.||.            |...|.||.|...|:.:.|.|..|.
Zfish   342 PSQPTQ----------------AHYSSY------------TASQSQSPASCPFKLAAGSKVLACP 378

  Fly   315 IGGETTSVVPVHPPTVSAQE 334
            :     :..||..|.||:|:
Zfish   379 L-----NACPVSAPGVSSQQ 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kni	NP_001287130.1	NR_DBD_like	8..92	CDD:413390	36/81 (44%)
nr1d4a	XP_021325494.1	NR_DBD_REV_ERB	111..199	CDD:143540	37/83 (45%)
		NR_LBD	382..570	CDD:472173	6/12 (50%)