Protein Alignment kni and Ar

DIOPT Version :10

• Sequence 1: NP_001287130.1
• Gene: kni / 40287
• FlyBaseID: FBgn0001320
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_036634.2
• Gene: Ar / 24208
• RGDID: 2147
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 136
• Identity: 45/136 - (33%)
• Similarity: 57/136 - (41%)
• Gaps: 32/136 - (23%)

  Fly     8 QTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCY 72
            :||.:||:.|:|.|:||.||..||.||.|:........ |.:...|.|||..|..|.:|||||||
  Rat   540 KTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYL-CASRNDCTIDKFRRKNCPSCRLRKCY 603

  Fly    73 NVGMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSASSPVGSP------ 131
            ..||:.|..:..:..|     ..|||.                   |...||.||...|
  Rat   604 EAGMTLGARKLKKLGN-----LKLQEE-------------------GENSSAGSPTEDPSQKMTV 644

  Fly   132 -HTPGF 136
             |..|:
  Rat   645 SHIEGY 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kni	NP_001287130.1	NR_DBD_like	8..92	CDD:413390	34/83 (41%)
Ar	NP_036634.2	Interaction with ZNF318. /evidence=ECO:0000250|UniProtKB:P19091	1..569		15/28 (54%)
		Modulating	1..540		45/136 (33%)
		Androgen_recep	6..443	CDD:426632
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..146
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..224
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	439..465
		Interaction with LPXN. /evidence=ECO:0000250|UniProtKB:P10275	534..901		45/136 (33%)
		NR_DBD_AR	537..618	CDD:143547	33/78 (42%)
		Interaction with HIPK3. /evidence=ECO:0000269|PubMed:9725910	554..644		36/114 (32%)
		Interaction with CCAR1. /evidence=ECO:0000250|UniProtKB:P10275	574..901		29/102 (28%)
		Interaction with KAT7. /evidence=ECO:0000250|UniProtKB:P10275	607..901		14/68 (21%)
		NR_LBD_AR	655..900	CDD:132758