Protein Alignment knrl and Hr4

DIOPT Version :9

• Sequence 1: NP_001303368.1
• Gene: knrl / 40285
• FlyBaseID: FBgn0001323
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001259161.1
• Gene: Hr4 / 31162
• FlyBaseID: FBgn0264562
• Length: 2123
• Species: Drosophila melanogaster
• Alignment Length: 886
• Identity: 168/886 - (18%)
• Similarity: 260/886 - (29%)
• Gaps: 325/886 - (36%)

  Fly    14 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECIINKKNRTACKACRLKKCLMV 78
            |.:|.:.|.|.|:|..||||||.||.|:..| ..:..|..:|.|.|.|..|..|:.||.|||:..
  Fly   921 CMICEDKATGLHYGIITCEGCKGFFKRTVQN-RRVYTCVADGTCEITKAQRNRCQYCRFKKCIEQ 984

  Fly    79 GM-------------SKSGSRYG---------RRSNWFKIHCLLQEQQQQAVAAM---------- 111
            ||             ..||:.|.         :::|..:.....|:|||||.|..
  Fly   985 GMVLQAVREDRMPGGRNSGAVYNLYKVKYKKHKKTNQKQQQQAAQQQQQQAAAQQQHQQQQQHQQ 1049

  Fly   112 -----------AAHHNSQQAGGGSSGGSGGGQGMPNGVKGMSGVPPP----------AAAAAALG 155
                       ..||:..|   |........|..|.       :.|.          |||.||
  Fly  1050 HQQHQQQQLHSPLHHHHHQ---GHQSHHAQQQHHPQ-------LSPHHLLSPQQQQLAAAVAA-- 1102

  Fly   156 MLGHPGGYPGLYAVANAGGSSRSKEELMMLGLDGSVE------YGSHKHP-VVASPSVSSPDSHN 213
                        |..:.....:.:::.....|.|.|.      .|....| ::.:|.:.||....
  Fly  1103 ------------AAQHQQQQQQQQQQQQQAKLMGGVVDMKPMFLGPALKPELLQAPPMHSPAQQQ 1155

  Fly   214 SDSSVEVSSVRGNPLLHLGGKSNSGGSSSGADGSH----SGGGGGGGGGVTPGRPPQMRKDLSPF 274
            .....:....:.:|.|.|...........|...:|    .|||||.|||..  .||.:.......
  Fly  1156 QQQQQQQQQQQASPHLSLSSPHQQQQQQQGQHQNHHQQQGGGGGGAGGGAQ--LPPHLVNGTILK 1218

  Fly   275 LPLPFPG--------------------------------LASMPVMPPPAFLP------------ 295
            ..|..|.                                |.....|...|.||
  Fly  1219 TALTNPSEIVHLRHRLDSAVSSSKDRQISYEHALGMIQTLIDCDAMEDIATLPHFSEFLEDKSEI 1283

  Fly   296 ----------------------PSHLLFP-GYHPALYSH--HQGLLKPTPEQQQAAVAAAAVQHL 335
                                  |.:|..| ..|..|.:.  |:.|:..|          ||.|.|
  Fly  1284 SEKLCNIGDSIVHKLVSWTKKLPFYLEIPVEIHTKLLTDKWHEILILTT----------AAYQAL 1338

  Fly   336 F---NSSGAGQRF-APGTSPFANHQQHHKEEDQPAPARSPSTHAN--------NNHL-------- 380
            .   ...|.|.|. :|.::|.:...........|:||:  ..|.:        |:||
  Fly  1339 HGKRRGEGGGSRHGSPASTPLSTPTGTPLSTPIPSPAQ--PLHKDDPEFVSEVNSHLSTLQTCLT 1401

  Fly   381 -------------LTNGGAADELTK------------------RFYL----------------DA 398
                         |..|...|::|:                  :.|:                ..
  Fly  1402 TLMGQPIAMEQLKLDVGHMVDKMTQITIMFRRIKLKMEEYVCLKVYILLNKAEVELESIQERYVQ 1466

  Fly   399 VLKSQQQSPPP------TTKLPPHSKQDYSISALVTP----------NSESGRERVKSRQNEEDD 447
            ||:|..|:..|      .::|..|..:..:.::|:..          ||.|.| ::...
  Fly  1467 VLRSYLQNSSPQNPQARLSELLSHIPEIQAAASLLLESKMFYVPFVLNSASIRXQMLEH------ 1525

  Fly   448 EARADGIIDGAEHDDEEEDLVVSMTPPHSP--------AQQEERTPAGEDPRPSPGQDNPIDLSM 504
                 |::..|.|..         .||..|        .||:||       |.|..|.:.:..::
  Fly  1526 -----GLLPTANHQS---------APPPGPDTIPERQQQQQQER-------RRSRQQQHQLLRNL 1569

  Fly   505 KTTGSSLSS------KSSSPEIEPETEISSDVEKNDTDDDDEDLK-------------VTPEEEI 550
            ......:.|      :.|..|:|.|.|...||:...:......||             :|...|.
  Fly  1570 PKIKIEIGSQRDPEEEESEQELEQEPEQEQDVQSRPSAASTSILKTSLLSGAAATLATLTAAAEQ 1634

  Fly   551 SVRETADPEIEEDHSSTTETAKTSIENTHNNNNSISNNNNNNNNNNNSILSDSEASETIKRKLDE 615
            ..|.:|..:...|:|.::.::..|...|.......|....::|:     |.:|:..|..:::..:
  Fly  1635 IARSSASCDTARDYSQSSNSSSNSNAATGATGTMASGRTGSSNS-----LEESKRLEHQQQQQQQ 1694

  Fly   616 LIEASSENGKRL-----------RLEAPVKVATSNALDLTT 645
            ..:......::.           |...|...|||.|..:|:
  Fly  1695 QQQPQQHQQQQYTSILHTALMSQRSMPPATSATSAAAAVTS 1735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	34/103 (33%)
Hr4	NP_001259161.1	NR_DBD_DHR4_like	913..1002	CDD:143542	30/81 (37%)
		NR_LBD_DHR4_like	1256..1515	CDD:132751	42/270 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48092
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100