DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment knrl and nhr-36

DIOPT Version :9

Sequence 1:	NP_001303368.1	Gene:	knrl / 40285	FlyBaseID:	FBgn0001323	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_001294717.2	Gene:	nhr-36 / 24104398	WormBaseID:	WBGene00017198	Length:	435	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	56/233 - (24%)
Similarity:	92/233 - (39%)	Gaps:	60/233 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECI--INKKNR-TACKACRL 72
            |:.|:|||:.:||.|:....|.||||||.|:..:.::..:||.:..|.  |::..| ..|:.|||
Worm    33 NEMCRVCGKNSAGKHYSVPACHGCKSFFRRAIIHKTAYPECKYDKMCFSKISRITRPRKCRYCRL 97

  Fly    73 KKCLMVGMSKSGSRYGRRSNWFKIHCLLQEQQQQAVAAMAAHHNSQQAGGGSSGGSGGGQGMP-- 135
            :||..|||                           ||.:|.|.....:...||........:|
Worm    98 QKCYEVGM---------------------------VAIVAMHRKHDDSPLRSSDSELPDLPLPSP 135

  Fly   136 -----NGVKGM------SGVPPPAAAAAALGMLGHPG-----GYPGLYAVANAGGS--------- 175
                 |.|.|:      ..:.......:|...|..|.     ..||..|:|:..|:
Worm   136 IATRENYVSGIIDKLHSLDIQTDKFRKSAYNPLFIPNLEGILASPGKLALADKYGAMPGWPLTQE 200

  Fly   176 SRSKEELMMLGLDGSV---EYGSHKHPVVASPSVSSPD 210
            |.::::::|..::|.|   ...|...|...:|.:::.|
Worm   201 SFNEQQILMNQVNGDVLTDSSSSFVLPTADTPGINTKD 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	29/86 (34%)
nhr-36	NP_001294717.2	ZnF_C4	36..105	CDD:197701	27/68 (40%)
nhr-36	NP_001294717.2	HOLI	242..400	CDD:214658
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000