Protein Alignment knrl and nhr-85

DIOPT Version :9

• Sequence 1: NP_001303368.1
• Gene: knrl / 40285
• FlyBaseID: FBgn0001323
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001021667.1
• Gene: nhr-85 / 191732
• WormBaseID: WBGene00003675
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 122/564 - (21%)
• Similarity: 182/564 - (32%)
• Gaps: 200/564 - (35%)

  Fly    14 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECIINKKNRTACKACRLKKCLMV 78
            |:||.:.|:|||:|.|.|||||.||.||.....:...|....:|:|.:.||..|:.|||||||.|
 Worm   113 CQVCSDKASGFHYGVFACEGCKGFFRRSIQQKITYRACTRAEDCLILRNNRNRCQCCRLKKCLAV 177

  Fly    79 GMSKSGSRYGRRSNWFKIHCLLQEQQQQAVAAM------------AAHHNSQQAGGGSSGGSGGG 131
            |||:...|:||.....|.. :.:|.|:..|.:.            ...|...||.|
 Worm   178 GMSRDAVRFGRVPKREKAR-MFEEMQKTNVQSQRDQIAIQYENLTEVMHKINQAFG--------- 232

  Fly   132 QGMPNGVKGMSGVPPPAAAAAALGMLGHPGGYPGLYAVANAGGSSRSKEELMMLGLDGSVEYGSH 196
                             ...|.|.....|     :|                           :.
 Worm   233 -----------------TLQATLEKCTGP-----IY---------------------------TD 248

  Fly   197 KHPVVAS----PSVSSPDSHNSDSSVEVSSVRGNPLLHLGGKSNSG------GSSSGADGSHSGG 251
            :.|:.::    |..::.|..||..:  ..|:.....:||  ..||.      .|:|.:...|
 Worm   249 RCPITSNFIVIPLKAAIDFANSIPA--FLSITQTQRVHL--LQNSVFDVMLLASASASTSQH--- 306

  Fly   252 GGGGGGGVTPGRPPQMRKDLSPFLPLPFPGLASMPVMPPPAFLPPSHLLFPGYHPALYSHHQGLL 316
                   ..||.....:...:|.:|.....:::.....||..:|   :|     .|:......||
 Worm   307 -------FPPGGLTYDQSSANPIIPQAIQSISARIRQLPPQTVP---IL-----TAIAVCQADLL 356

  Fly   317 KPTPEQQQAAVAAAAVQHLFNSSGAGQRFAPGTSPFAN----HQQHHKEEDQPAPARSPSTHANN 377
               ||.||..:.|..:..:....|..|..|...|..|:    .|.|   .|:.......|.|.:.
 Worm   357 ---PESQQPMLLAERLWCVLGKLGGIQSLATAPSLLADVRTLRQWH---SDRLRQMSQISQHFSQ 415

  Fly   378 NHLLTNGGAADELTKRFYLDAVLKSQQQSP---PPTTKLPPHSKQDYSISALVTPNSESGRERVK 439
            |.|:....||                  :|   ||....||       .||..|.:|....|.:
 Worm   416 NLLIAPVAAA------------------APVLLPPAFLSPP-------ASATSTSSSSVKSEFI- 454

  Fly   440 SRQNEEDDEARADGIIDGAEHDDEEEDLVVSMTPPHSPAQQEERTPAGEDPR--PSPGQDNPIDL 502
                                   |....:.|:.               |.||  .|.|...|::|
 Worm   455 -----------------------ERHPSIASLL---------------ERPRRISSSGAQEPLNL 481

  Fly   503 SMKTTGSSLSSKSSSPEIEPETEISSDVEKNDTDDDDEDLKVTP 546
            |:             |.:  ..::..||   |:|:..|::||:|
 Worm   482 SL-------------PHV--RHQVKRDV---DSDEQLEEMKVSP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	38/81 (47%)
nhr-85	NP_001021667.1	NR_DBD_REV_ERB	110..196	CDD:143540	39/82 (48%)
		HOLI	261..>369	CDD:214658	27/132 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3340
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960