DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment knrl and nhr-95

DIOPT Version :9

Sequence 1:	NP_001303368.1	Gene:	knrl / 40285	FlyBaseID:	FBgn0001323	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_001024229.1	Gene:	nhr-95 / 180254	WormBaseID:	WBGene00003685	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	40/169 - (23%)
Similarity:	64/169 - (37%)	Gaps:	49/169 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YAMNQTCKVCG-EPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECIINKKNRTA--CKA 69
            :.:.|.|::|. :...|.|||..:|..|.:||.|:.|:..|...|. .|.|     |:.:  ||.
Worm     8 HILPQKCEICKIQKCHGNHFGVNSCRACAAFFRRTVNSKWSRMRCL-GGSC-----NQISFLCKP 66

  Fly    70 CRLKKCLMVGMSKSGSRYGRRSNWFKIHCLLQEQQQQAVA------------AMAAHHNSQQA-- 120
            |||::|...||..:..:|.|     .:.|.:..|...::.            .|.:..||::.
Worm    67 CRLQQCFNGGMMTNNFQYNR-----DVICPMDPQPTVSIPKSLEIYLGKPYFVMLSEKNSEKTEI 126

  Fly   121 ---------------GGGSSGGSGGGQ------GMPNGV 138
                           |..|.....|.|      |:||.:
Worm   127 DLHRLLGEASKILSQGSASPSFCAGNQLKKLSLGLPNQI 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	28/86 (33%)
nhr-95	NP_001024229.1	ZnF_C4	13..80	CDD:197701	25/72 (35%)
nhr-95	NP_001024229.1	Hormone_recep	168..366	CDD:278530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1136195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010