DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hao1 and CG18003

DIOPT Version :9

Sequence 1:	NP_001077011.1	Gene:	hao1 / 402827	ZFINID:	ZDB-GENE-060519-2	Length:	369	Species:	Danio rerio
Sequence 2:	NP_001027401.1	Gene:	CG18003 / 3771779	FlyBaseID:	FBgn0061356	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	182/361 - (50%)
Similarity:	249/361 - (68%)	Gaps:	9/361 - (2%)

- Green bases have known domain annotations that are detailed below.

Zfish     4 ALVCVRDYELRARQILPKSVFDYYFSGADEQETLRDNVAAFKRWCFYPRVLRDVSSVDLSTTVLG 68
            |||||.|:|.:|...|.|:..|||.|||.||.||..|..||:|....||.|||||.:|:||.:.|
  Fly     2 ALVCVEDFEKKAVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIFG 66

Zfish    69 QRVSLPICVSATAMQRMAHPDGETATARACLSSGTGMMLSSWSTSSIEEVCEAAPGAVRWLQLYI 133
            :::..|:.::.||||:|||||||...|||...:|:..:||:.||:|:|::...||..::|.||||
  Fly    67 EQMQWPLGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLYI 131

Zfish   134 YKDRGLTQSLVRRAEDAGYKGIFVTVDTPYLGRRRDDVRNRFKLPSHLRMANFESPDLAFSKKEG 198
            ||||.:|:.||||||.|.:|.:.:|:|.|..|.||.||||.|.|||||.:|||:.     .|..|
  Fly   132 YKDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQG-----VKATG 191

Zfish   199 YGE----DSGLAVYVTQAIDATVRWQDIGWLKTLTKLPVVVKGVLTAEDAKEALKYGVDGILVSN 259
            .|.    .||:..||:...|.|:.|:||.|||.:|.||:|||||||||||..|.::|..|::|||
  Fly   192 VGNAAMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGLIVSN 256

Zfish   260 HGARQLDGVPATIDALPEVVAAVAGQVEVFMDGGVRMGSDVLKALALGAKAVFIGRPVLWALACQ 324
            |||||:|.|||:|:||||:|.||...:.|.:|||:..|:|:.||||||||.||:|||.:|.||..
  Fly   257 HGARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGRPAVWGLAYN 321

Zfish   325 GEKGVSDVLEILREELHLALALAGCRSLKEVNRSLL 360
            |:|||.::|.:||::....:||.||::|.::..:::
  Fly   322 GQKGVEEMLSVLRKDFETTMALIGCQNLGDITSAMV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hao1	NP_001077011.1	alpha_hydroxyacid_oxid_FMN	10..357	CDD:239203	177/350 (51%)
hao1	NP_001077011.1	FMN_dh	16..362	CDD:279418	174/349 (50%)
CG18003	NP_001027401.1	alpha_hydroxyacid_oxid_FMN	7..353	CDD:239203	177/350 (51%)
CG18003	NP_001027401.1	FMN_dh	17..359	CDD:279418	174/346 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573411
Domainoid	1	1.000	356	1.000	Domainoid score	I947
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6578
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2098
OMA	1	1.010	-	-		QHG54906
OrthoDB	1	1.010	-	-		D500918at33208
OrthoFinder	1	1.000	-	-		FOG0001123
OrthoInspector	1	1.000	-	-		otm24945
orthoMCL	1	0.900	-	-		OOG6_100930
Panther	1	1.100	-	-	LDO	PTHR10578
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X693
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910