DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4858 and nubp2

DIOPT Version :9

Sequence 1:	NP_649243.1	Gene:	CG4858 / 40282	FlyBaseID:	FBgn0037011	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001032191.2	Gene:	nubp2 / 641290	ZFINID:	ZDB-GENE-051023-10	Length:	269	Species:	Danio rerio

Alignment Length:	259	Identity:	144/259 - (55%)
Similarity:	189/259 - (72%)	Gaps:	2/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LDKVKNVIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDD 66
            ||:||:|::||||||||||||::|:|:||.|..|.|||:||:||||||:|.:|.:...::.|||.
Zfish     9 LDQVKHVLLVLSGKGGVGKSTITTELALAFRHAGKKVGILDVDLCGPSIPRMLSVGKPEVHQCDS 73

  Fly    67 GWVPVYTD--ESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGT 129
            ||||||.|  :.|.||:|||.|||::.::.|||||||||.:|.||::||.|.|||.|::||||||
Zfish    74 GWVPVYADPQQQQQLALMSIAFLLEDSDEAVIWRGPKKTALIGQFVSDVAWGELDILLVDTPPGT 138

  Fly   130 SDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSC 194
            ||||:.|:|.|::....||::|||||.|:..|||:||||||||.:.||||||||||||||||:.|
Zfish   139 SDEHLAVLENLRKHRVDGAVLVTTPQAVSTGDVRREITFCKKTNLKILGIVENMSGFVCPHCSEC 203

  Fly   195 TNIFSSNGGVSLATYAQVPHLGTLPIDPRVGILAGTTTSVLDELPDSTTAEVLTHIVEKLKTML 258
            :||||..||..||.......||::|:||.:..........|...|:|:|...::||...|...|
Zfish   204 SNIFSKGGGEELAKLTGSAFLGSVPLDPLLTESLEEGRDFLQAFPESSTFTAISHIANTLLNSL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4858	NP_649243.1	ParA	4..254	CDD:287566	140/251 (56%)
CG4858	NP_649243.1	minD_arch	8..254	CDD:131024	138/247 (56%)
nubp2	NP_001032191.2	ParA	11..264	CDD:287566	140/252 (56%)
nubp2	NP_001032191.2	minD_arch	15..263	CDD:131024	138/247 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585918
Domainoid	1	1.000	296	1.000	Domainoid score	I1452
eggNOG	1	0.900	-	-		E1_COG0489
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8057
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2670
OMA	1	1.010	-	-		QHG53899
OrthoDB	1	1.010	-	-		D1166096at2759
OrthoFinder	1	1.000	-	-		FOG0001227
OrthoInspector	1	1.000	-	-		oto38975
orthoMCL	1	0.900	-	-		OOG6_100169
Panther	1	1.100	-	-	LDO	PTHR23264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R189
SonicParanoid	1	1.000	-	-		X4074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800