DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4858 and Nubp2

DIOPT Version :9

Sequence 1:	NP_649243.1	Gene:	CG4858 / 40282	FlyBaseID:	FBgn0037011	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_036086.1	Gene:	Nubp2 / 26426	MGIID:	1347072	Length:	275	Species:	Mus musculus

Alignment Length:	250	Identity:	136/250 - (54%)
Similarity:	193/250 - (77%)	Gaps:	0/250 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VKNVIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDDGWV 69
            |:::|:||||||||||||:||:|:||||..|.|||:||:||||||:|::|..:|:.:.|||:|||
Mouse    17 VRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLRAQGKAVHQCDNGWV 81

  Fly    70 PVYTDESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHI 134
            ||:.|:.|::::||:||||:|.::.|:||||||..:|:||::||.|.:||||::||||||||||:
Mouse    82 PVFVDQEQSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDEHM 146

  Fly   135 TVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSCTNIFS 199
            ..||.|:.....||::|||||.|::.|||:|:|||||||:.::|::||||||.||||..|||:||
Mouse   147 ATMEALRPYRPLGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFS 211

  Fly   200 SNGGVSLATYAQVPHLGTLPIDPRVGILAGTTTSVLDELPDSTTAEVLTHIVEKL 254
            |..|..||..|.||.||::|:|.::..........:.|.|.||....||.|.:::
Mouse   212 SGSGEELARLAGVPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRV 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4858	NP_649243.1	ParA	4..254	CDD:287566	136/248 (55%)
CG4858	NP_649243.1	minD_arch	8..254	CDD:131024	135/245 (55%)
Nubp2	NP_036086.1	ParA	17..266	CDD:313763	136/248 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841574
Domainoid	1	1.000	312	1.000	Domainoid score	I1312
eggNOG	1	0.900	-	-		E1_COG0489
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8057
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2566
Isobase	1	0.950	-	0	Normalized mean entropy	S504
OMA	1	1.010	-	-		QHG53899
OrthoDB	1	1.010	-	-		D1166096at2759
OrthoFinder	1	1.000	-	-		FOG0001227
OrthoInspector	1	1.000	-	-		oto95250
orthoMCL	1	0.900	-	-		OOG6_100169
Panther	1	1.100	-	-	LDO	PTHR23264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R189
SonicParanoid	1	1.000	-	-		X4074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750