DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)77CDf and Ptdss2

DIOPT Version :9

Sequence 1:	NP_649242.1	Gene:	l(3)77CDf / 40281	FlyBaseID:	FBgn0287585	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001099786.1	Gene:	Ptdss2 / 293620	RGDID:	1307914	Length:	471	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	139/391 - (35%)
Similarity:	213/391 - (54%)	Gaps:	36/391 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KRRDGSDGSVSS-AGARRKRKDEIAQTFVIVNERPVDDISLDFFYKPHTITLLAVSVLAVMYFAF 112
            :|..|..||.|. ...||..:.|:           .||.:..||::.||:|:|.:...|:.|...
  Rat     6 RRVAGGSGSESPLLEGRRSTESEV-----------YDDGTNTFFWRAHTLTVLFILTCALGYVTL 59

  Fly   113 VRNEANVDE--NLWAGLLCIVFFFLIVSVIAFPNGPFTRPHPAVWRILFGCSVLYLLTLQFLMFQ 175
            : .|...|.  |...|::..:..||...|....:|||:|||||.||.....||:|.|.|.|::||
  Rat    60 L-EETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQ 123

  Fly   176 NYPTIRSIFYWIDPKLKNFHIDM-EKEYGVNC----SDIS-------WDRVKGHLDVFAWGHFLG 228
            .....|....::||:|   .:.: |::||.||    :|..       ||:    ||.|...||:|
  Rat   124 TVHDGRQFLKYVDPRL---GVPLPERDYGGNCLIYDADNKTDPFHNIWDK----LDGFVPAHFIG 181

  Fly   229 WAFKAILIRHMGILWAISVMWEITEITFAHLLPNFIECWWDALILDVIICNGLGIWMGLKICQIL 293
            |..|.::||...:...||||:|..|.:..|.||||.|||||..|:||::||||||:.|:|..:.|
  Rat   182 WYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLLCNGLGIYCGMKTLEWL 246

  Fly   294 EMREYKWASIKDISTTTGKIKRAMLQFTPESWSAIRWLDPKSTAMRFAAVIQLVIFWQVTELNTF 358
            .::.|||..:.:|.|..||:||...||||.||....| .|.|:..|:.||..:::.:.:.|||||
  Rat   247 SLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEW-KPASSLHRWLAVCGIILVFLLAELNTF 310

  Fly   359 FLKHIFEMPPDHFIVIGRLIFIGLFVAPSVRQYYVYVTDTR-CKRVGTQCWVYGAIMVSEAILCI 422
            :||.:..|||:|::|:.||:|.......::|:.|.::.:.: .:::|.|.|:..||.|:|.::.:
  Rat   311 YLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDELKPHRKLGQQAWLVAAITVTELLIVV 375

  Fly   423 K 423
            |
  Rat   376 K 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)77CDf	NP_649242.1	PSS	150..425	CDD:397256	110/287 (38%)
Ptdss2	NP_001099786.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		7/19 (37%)
		PSS	98..378	CDD:397256	110/287 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..471
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2735
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D370266at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101724
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720