DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mTerf3 and MTERF1

DIOPT Version :9

Sequence 1:	NP_649240.1	Gene:	mTerf3 / 40279	FlyBaseID:	FBgn0037008	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_008911.1	Gene:	MTERF1 / 7978	HGNCID:	21463	Length:	399	Species:	Homo sapiens

Alignment Length:	195	Identity:	47/195 - (24%)
Similarity:	94/195 - (48%)	Gaps:	17/195 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LDFEKNVKPYITFLVDQGVSPDDFGRMFTKNPLLFKEDLDDLQTRVNYLKSKRFS----DEAR-- 177
            |:.|.|:|    ||...|::.....|:.|..|..|...||..:..|.:|::...|    |.|.
Human   174 LNLENNIK----FLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAGLSLGHNDPADFV 234

  Fly   178 QRILTQNPYWLMFSTRRVDRRLGYFQKEFKLSGHDLRLLATREPNA--ITYNMEHLRKSVFTLKE 240
            ::|:.:||:.|:.||:||...:.:.:..|.|:..:|.:|.. .|.|  :..:.::.|:|...:||
Human   235 RKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLVLIC-GPGAEILDLSNDYARRSYANIKE 298

  Fly   241 E---MGFNAKELSDLVVRKPRLLMIPPDDLVERFSYIHQDMGLPHAQIVQCPELLASREFRLRER 302
            :   :|...:|:...|:..|.::.:......::...:.:: .:..:||::.|.:|.|....|:.|
Human   299 KLFSLGCTEEEVQKFVLSYPDVIFLAEKKFNDKIDCLMEE-NISISQIIENPRVLDSSISTLKSR 362

Fly 303 302
Human 363 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mTerf3	NP_649240.1	mTERF	<122..307	CDD:327630	46/192 (24%)
MTERF1	NP_008911.1	mTERF	76..389	CDD:280667	47/195 (24%)
		Interaction with DNA	169..170
		Interaction with DNA	247..251		2/3 (67%)
		Interaction with DNA	324..331		0/6 (0%)
		Interaction with DNA	355..358		0/2 (0%)
		Interaction with DNA	384..391
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1267
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810