Protein Alignment CG5078 and SGE1

DIOPT Version :10

• Sequence 1: NP_649238.3
• Gene: CG5078 / 40276
• FlyBaseID: FBgn0037005
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_015524.1
• Gene: SGE1 / 856327
• SGDID: S000006402
• Length: 543
• Species: Saccharomyces cerevisiae
• Alignment Length: 482
• Identity: 100/482 - (20%)
• Similarity: 171/482 - (35%)
• Gaps: 151/482 - (31%)

  Fly    27 ILVVVFLEYFAWGLLTMPMIATLKET--FPDHTFLMNGLVMGVKGILSFLSSPLIGALSDIYGRK 89
            :|:.:||     ..|.:.::.||.:|  ...|.|...|.::....:.:.:...|.|.|::|.|.|
Yeast    14 LLLTLFL-----AALDIVIVVTLYDTIGIKFHDFGNIGWLVTGYALSNAVFMLLWGRLAEILGTK 73

  Fly    90 VLLLITVIFTSLPIPMMTMDNWWFFVISS--ISGVLGVSFSVAFAYVADVTTKEERSRSYELVSA 152
            ..|:|:||...:...:..:.|....:||.  ::| .|.|...:.|:|...:...|..|.  ::..
Yeast    74 ECLMISVIVFEIGSLISALSNSMATLISGRVVAG-FGGSGIESLAFVVGTSIVRENHRG--IMIT 135

  Fly   153 TFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRSTGLSWKQADPF 217
            ..|.|.|||..:|..|...:                                 :..|||:..  |
Yeast   136 ALAISYVIAEGVGPFIGGAF---------------------------------NEHLSWRWC--F 165

  Fly   218 LSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTEL----------STLVAFM 272
            .....:|:    ....::.|.....|..:...:|:.:|..|.:|:.||          ..||..:
Yeast   166 YINLPIGA----FAFIILAFCNTSGEPHQKMWLPSKIKKIMNYDYGELLKASFWKNTFEVLVFKL 226

  Fly   273 AILGI---SINVTLGSIVKTLGAKN------AIILGLLLELLQLILFAIGYEKWQMWLAG----- 323
            .::||   |...||..:..:.|..|      .||....:..:.|:||. .|:...:.|:|
Yeast   227 DMVGIILSSAGFTLLMLGLSFGGNNFPWNSGIIICFFTVGPILLLLFC-AYDFHFLSLSGLHYDN 290

  Fly   324 ---------NVAA------------LSSITFPAVSAY-VSLYTDVETQG-----------AVQGM 355
                     |:|:            ||...:...||| |.||..|..:.           ::..|
Yeast   291 KRIKPLLTWNIASNCGIFTSSITGFLSCFAYELQSAYLVQLYQLVFKKKPTLASIHLWELSIPAM 355

  Fly   356 ITGMS--------GLCSGLGPAL-FGI--------VFYLSDMDLDKN---RILIGSVSGDRTVTN 400
            |..|:        |:   :.||: ||:        :|.|.:.:|.::   .||.|...|
Yeast   356 IATMAIAYLNSKYGI---IKPAIVFGVLCGIVGSGLFTLINGELSQSIGYSILPGIAFG------ 411

  Fly   401 PFMIGAISVFIGILLASYI------PD 421
                   |:|...||:|.:      ||
Yeast   412 -------SIFQATLLSSQVQITSDDPD 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5078	NP_649238.3	MFS_MFSD14	24..420	CDD:340945	98/479 (20%)
SGE1	NP_015524.1	MFS_Azr1_MDR_like	24..531	CDD:341045	96/467 (21%)