Protein Alignment CG5078 and SLC46A1

DIOPT Version :9

• Sequence 1: NP_649238.3
• Gene: CG5078 / 40276
• FlyBaseID: FBgn0037005
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_542400.2
• Gene: SLC46A1 / 113235
• HGNCID: 30521
• Length: 459
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 87/415 - (20%)
• Similarity: 161/415 - (38%)
• Gaps: 101/415 - (24%)

  Fly    51 ETFPDH-TFLMN--GLVMGVKGILSFLSSPLIGALSDIYGRKVLLLITVI------FTSLPIPMM 106
            ||...| |..||  |.::|:      .||.|:||.||..||:.||::..:      ..|:.:..:
Human    79 ETLTSHWTLYMNVGGFLVGL------FSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQL 137

  Fly   107 TMDNWWFF---VISSISGVLGVSFSVAFAYVADVTTKEERSRSYELVSATFAASLVIAPAMGN-- 166
            .:...:|.   ::.::.|..|...:.:||.||||::...|:....|:.|:...:.::|..:|.
Human   138 QLHVGYFVLGRILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHW 202

  Fly   167 LIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRSTGLSWKQADPFLSLRRVGSDP---- 227
            |....|.....:.:|.|::.|  ::......|||::...:...:::.....:.| .|...|
Human   203 LRAQGYANPFWLALALLIAMT--LYAAFCFGETLKEPKSTRLFTFRHHRSIVQL-YVAPAPEKSR 264

  Fly   228 -NVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFMAILGISINVTLGSIVKTLG 291
             ::.|..:.:|..:....|....:..|          ||||.:.:.:.|     :..||..:.|.
Human   265 KHLALYSLAIFVVITVHFGAQDILTLY----------ELSTPLCWDSKL-----IGYGSAAQHLP 314

  Fly   292 AKNAII----------------LGLLLELLQLILFAIGYEKWQMWLAGNVAALSSITFPAVSAYV 340
            ...:::                :||...:|.:::||.......|:....:..||.:..|.:.|.:
Human   315 YLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYGLLFLSLVITPVIRAKL 379

  Fly   341 SLYTDVETQGAV---------QGMITGMSGLCSGLGPALFGIV--FYLSDMDLDKNRILIGSVSG 394
            |.......|||:         ..|:|. ||:.:.|.||....:  |
Human   380 SKLVRETEQGALFSAVACVNSLAMLTA-SGIFNSLYPATLNFMKGF------------------- 424

  Fly   395 DRTVTNPFMIGA-----ISVFIGIL 414
                  ||::||     .:|.||:|
Human   425 ------PFLLGAGLLLIPAVLIGML 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5078	NP_649238.3	MFS	27..375	CDD:119392	78/369 (21%)
		MFS_1	27..368	CDD:284993	76/360 (21%)
SLC46A1	NP_542400.2	MFS	73..443	CDD:119392	86/413 (21%)
		MFS_1	94..407	CDD:284993	66/337 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810