DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5078 and mfsd14bl

DIOPT Version :9

Sequence 1:	NP_649238.3	Gene:	CG5078 / 40276	FlyBaseID:	FBgn0037005	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001135533.1	Gene:	mfsd14bl / 100216076	XenbaseID:	XB-GENE-22168215	Length:	475	Species:	Xenopus tropicalis

Alignment Length:	433	Identity:	216/433 - (49%)
Similarity:	301/433 - (69%)	Gaps:	20/433 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LKKLLVSLAST-SGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKG 69
            :|::|:....| .|||:|||.|.:||:|||:|||||||.||:..|.||||.||||||||:.||||
Frog     3 VKRILMKEGGTHQGIGRPSVYHAVVVIFLEFFAWGLLTTPMLVVLHETFPQHTFLMNGLIQGVKG 67

  Fly    70 ILSFLSSPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYV 134
            .|||:.:||||||||:||||..||:||.||..|||:|.:..||:|.:.|:||...|:|||.||||
Frog    68 FLSFMCAPLIGALSDVYGRKSFLLLTVFFTCFPIPLMRISPWWYFAMISVSGAFSVTFSVIFAYV 132

  Fly   135 ADVTTKEERSRSYELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPET 199
            ||:|.:.|||.:|.|||||||||||.:||:|..|.:.||.|.||||||:|:..::.|:||||||:
Frog   133 ADITQEHERSTAYGLVSATFAASLVTSPAIGAYISEFYGDNLVVLVATVVALLDICFILLAVPES 197

  Fly   200 LQQNVRST----GLSWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGF 260
            |::.:|.|    .:||:|||||.||:::|.|..|||:|:.:|...|||||:|||...||:..:||
Frog   198 LREKMRPTTWGAPISWEQADPFASLKKIGKDTTVLLICITVFLSYLPEAGQYSSFFLYLRQIIGF 262

  Fly   261 DFTELSTLVAFMAILGI-SINVTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGN 324
            :...::..:|.:.||.| :..|.|..:::::|.||.::|||..::.||..:..|.:.|.||.||.
Frog   263 NSGSIAAFIAVVGILSIVAQTVLLSILMRSIGNKNTVLLGLGFQMFQLAWYGFGSQPWMMWAAGA 327

  Fly   325 VAALSSITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILI 389
            |||:||||||||||.:|...:.:.||..|||:||:.|||:||||||:|.||:|..::|:.   ::
Frog   328 VAAMSSITFPAVSALISRNAESDQQGVAQGMVTGIRGLCNGLGPALYGFVFFLFHVELNG---IV 389

  Fly   390 GSVSGDRTVTN-----------PFMIGAISVFIGILLASYIPD 421
            ...|.|:...:           ||:.||.:|.:..|:|.:||:
Frog   390 PVPSSDKPENDPSDSTSVIPGPPFLFGACAVLLAFLVALFIPE 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5078	NP_649238.3	MFS	27..375	CDD:119392	191/352 (54%)
CG5078	NP_649238.3	MFS_1	27..368	CDD:284993	186/345 (54%)
mfsd14bl	NP_001135533.1	MFS	25..378	CDD:119392	191/352 (54%)
mfsd14bl	NP_001135533.1	MFS_1	27..371	CDD:284993	186/343 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D139531at33208
OrthoFinder	1	1.000	-	-		FOG0001490
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010