DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17637 and CG42514

DIOPT Version :9

Sequence 1:	NP_649237.1	Gene:	CG17637 / 40275	FlyBaseID:	FBgn0037004	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	94/530 - (17%)
Similarity:	203/530 - (38%)	Gaps:	132/530 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 WHAVIVT------FMHYFSWGLLTV---------------PFIEKL--------SGSFGNRVLLV 61
            ||.|..|      |::.|::.:.:|               .|.|::        :..|..:.:|.
  Fly    51 WHVVKSTSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAMLT 115

  Fly    62 DGLVYGVRGILGFVTTPV-----MGAISDFHGRKVVMLLAVATTYAPIPFMMLK---SWW----- 113
            :........|...| .|:     :|:.||..|||:.:|:.:...:.....:::.   :.|
  Fly   116 NAWFLQWENISAHV-FPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNI 179

  Fly   114 FFAILTVSSICG---STYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGS 175
            .::....|::.|   :.::|..||::|.::::.|:.....:...:.:.:....:||::|..:..:
  Fly   180 IYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFN 244

  Fly   176 ASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGK 240
            .|...:.|:...:..|.||:.:   ..||.:                   .:|:::
  Fly   245 QSYADMFTVNASLLALAIIYTL---CALKWQ-------------------TTPRQR--------- 278

  Fly   241 VNVEVNKPTSQNIVTNKELDQQFSKEE----NLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKD-- 299
                                   |..|    ....|..:|:.:       .|...||.|.||.
  Fly   279 -----------------------SLRELGCCGFWGDFFDKQHV-------KDSLAVLVKPRKGHR 313

  Fly   300 KNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYE--EVSMMLGLLSVLAITSNILLGYIMN- 361
            ::.|:|.|:: ::::.|.. |....:|:.|...|:::  ..|......|...:.:.:|...:||
  Fly   314 RSFLIILLVS-MALYTFQR-DEGQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNK 376

  Fly   362 IVGAKWS----IRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNR 422
            |:|  |.    |.:|.....:..|||.|.|:..:.:..:::.:|..|:.....|:.|.......|
  Fly   377 ILG--WRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSER 439

  Fly   423 GAVLGIISGIECLSEGVGPAFFGLLFF-IFQDDSETDLKVNSPISMPFVISAISVFVAIV-LSSF 485
            |.|..::|    :.:...|...|:.:. :::....|:...|  :.:..:.:.|:|||.|: |...
  Fly   440 GKVFALLS----VCDNAVPFISGVCYSQLYRRTQNTNHGGN--VFILTIATQIAVFVMILCLHIV 498

  Fly   486 IKKDTLGNEE 495
            :.|::|...|
  Fly   499 LGKNSLAVPE 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:119392	91/520 (18%)
CG17637	NP_649237.1	MFS_1	30..441	CDD:284993	78/468 (17%)
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	70/398 (18%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	76/433 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840