Protein Alignment CG17637 and VBA1

DIOPT Version :10

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_013806.1
• Gene: VBA1 / 855113
• SGDID: S000004694
• Length: 562
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 100/516 - (19%)
• Similarity: 182/516 - (35%)
• Gaps: 152/516 - (29%)

  Fly    78 PVMGAISDFHGRKVVMLLA--------VATTYAPIPFMMLKSWWFFAILTVSSIC-----GSTYS 129
            |:.|.:||..|||..:|.|        :.|.:|       ::...|:|  ..:||     |....
Yeast    89 PLYGKLSDITGRKSALLTAQFFFGLGCLLTCFA-------RNVTEFSI--ARAICGIGAGGLNAI 144

  Fly   130 SSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYG-------SASVILIATITGM 187
            ||:| |:|..|...|....|:....||.|......||...:::.|       ...||::.::..:
Yeast   145 SSIA-VSDICTARERGVYQGYANIVFGFGQLLGAPLGGVFIETIGWRALFGIQVPVIMLCSVLAI 208

  Fly   188 INILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGE-GKVNVEVNKP--- 248
            .||...:|.||.   :||:..:.|.        :::|..........::|. ...:.::||.
Yeast   209 KNINIKLFHVPP---MKERYTLKNL--------SRIDIFGSLSLVATISGVLFLCSSQLNKLYLA 262

  Fly   249 --TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFL 311
              |..:.:....:::.::.|:.|.                   :|:|.:|     ..:...:|.:
Yeast   263 LFTIGSFIVFILVERYYATEKILP-------------------FELLTRS-----FCLSSAVTVI 303

  Fly   312 SIWPFAGVDSTAPVYL---------KTNMGFEYEEVSMMLGLLSVLAITSN------------IL 355
            |.:...|....:|:||         ||.:...:..:|:.:|.|....:..|            |.
Yeast   304 SSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPSISVAVGSLVTGWVLRNTKINLAHCAYQIIF 368

  Fly   356 LGYIMNIVGAKWSIRLGLLLL-----------FLQMLFFGFGTHHW--MYWLSSIL--------- 398
            .|.||.::|    :.||..||           .|:.:.|...:..|  :|..:|:|
Yeast   369 GGMIMQLLG----LGLGYFLLSHLNPDYTIYDMLESITFRSNSIWWKLIYVFASVLVSFGYACLL 429

  Fly   399 -AALATII----PAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDS--- 455
             |.|.:|:    .:....:..::....:.|.|||....:......:....:..:|...:||.
Yeast   430 VATLVSIVFTVEKSQQGTMTGVFYLWRSIGNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHF 494

  Fly   456 --------------------ETDL--KVNSPISMPFVISAIS----VFVAIVLSSFIKKDT 490
                                .||:  ::.......|:||.|.    ..|.||||.::.|.|
Yeast   495 TKKQYYSLINDSSYLRGPNFPTDIFVRILDVYKKAFLISYIPNIALAAVGIVLSLYLVKHT 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:475125	98/511 (19%)
VBA1	NP_013806.1	MFS_Azr1_MDR_like	42..469	CDD:341045	84/428 (20%)