Protein Alignment CG17637 and QDR1

DIOPT Version :10

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_012146.1
• Gene: QDR1 / 854686
• SGDID: S000001382
• Length: 563
• Species: Saccharomyces cerevisiae
• Alignment Length: 489
• Identity: 105/489 - (21%)
• Similarity: 174/489 - (35%)
• Gaps: 151/489 - (30%)

  Fly    33 FMHYFS-------WGLLTVPFIEK---LSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFH 87
            |..:||       :.:||:  ||:   ::....|..::|..:..|       |...:||.::|..
Yeast    77 FTGFFSTVAGSIYYPVLTI--IERKFNITEELANVTIVVYFIFQG-------VAPSIMGGLADTF 132

  Fly    88 GRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLA------------------Y 134
            ||:.::|.|:..             :|.|.:.::  |...|:..||                  .
Yeast   133 GRRPIVLWAILA-------------YFCACIGLA--CAHNYAQILALRCLQAAGISPVIAINSGI 182

  Fly   135 VADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPE 199
            :.|.||...|....|.||.....|.||...:|..|...:|..::.....|...|.::|....:||
Yeast   183 MGDVTTKVERGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLVFSTLLMPE 247

  Fly   200 ---SLV---------LKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVNVEVNKPTSQN 252
               :||         ...:.:||:..:..|.  ..:||..|    |.|  |.:.:|:...|.  .
Yeast   248 TKRTLVGNGSVTPRSFLNRSLILHVGSVKKT--LHLDDPDP----ETL--EPRTSVDFLAPL--K 302

  Fly   253 IVTNKELD-------QQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYL-IT 309
            |:..:|:|       .|||.....|..||                .||.|.   .||.|..: :.
Yeast   303 ILHIREIDILLSIAGLQFSTWTTHQTALT----------------IVLSKK---YNLSVAKIGLC 348

  Fly   310 FLSIWPFAGVDSTAPV-----YL---------KTNMGFEYEEVSMM---LGLLSVLA--ITSNIL 355
            ||.    ||:.:...:     ||         |.|...:.:|:.:|   .|..:.:|  |.||
Yeast   349 FLP----AGISTLTSIISAGRYLNWSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSN-- 407

  Fly   356 LGYIMNIVGAKWSIRLGLLLLFLQML-FFGFGTHHWMYWLSSILAALATIIPAANNAVASIYAS- 418
            ..|..|:|.|:  :....:.|.|..: |..||      |..|:...||.::  ..:|.||::::
Yeast   408 SHYAFNLVEAR--LHPAFVTLLLSSIGFTAFG------WCISVKTPLAAVL--CTSAFASLFSNC 462

  Fly   419 -------------PDNRGAVLGIISGIECLSEGV 439
                         |.......|.::...||...:
Yeast   463 ILTFSTTLIVDLFPSKASTATGCLNLFRCLLSAI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:475125	105/489 (21%)
QDR1	NP_012146.1	MFS_Tpo1_MDR_like	72..516	CDD:340881	105/489 (21%)