Protein Alignment CG17637 and VBA5

DIOPT Version :10

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_013031.3
• Gene: VBA5 / 853980
• SGDID: S000001813
• Length: 582
• Species: Saccharomyces cerevisiae
• Alignment Length: 587
• Identity: 101/587 - (17%)
• Similarity: 171/587 - (29%)
• Gaps: 253/587 - (43%)

  Fly    25 VW--HAVIVTFMHYFSWGLLTV---PFIEKLSGSFGNRVLLVDGLVYGVRG----ILGFVTTPVM 80
            :|  .|.|:.|.|.....:|..   ..|..|:.|.  .:|:...:|.||.|    .|.||....|
Yeast    91 IWGRFASIIGFQHSLILAILIFEAGSLIAALASSM--NMLIFGRVVAGVGGSGLQTLCFVIGCTM 153

  Fly    81 GAISDFHGRKVVMLL----AVATTYAPI---PFMMLKSW-WFF---------------------- 115
              :.:.....|:.:|    |||....||   .|....:| |.|
Yeast   154 --VGERSRPLVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAEN 216

  Fly   116 ---------AILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFG-----AGIAFSPSLG 166
                     ||.|:||...|.:...:.:......:..:...:||...|.|     .|:.|.   |
Yeast   217 KGILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFG---G 278

  Fly   167 NYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEK 231
            |  ..|:.|..||...    ::.:|..||::.....|.:|   .|...||
Yeast   279 N--KYSWNSGQVITYL----VLGVLLFIFSLVYDFFLFDK---FNPEPDN--------------- 319

  Fly   232 KENLNGEGKVNVEVNKPTSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKS 296
                                  ::.:.|                                :||:.
Yeast   320 ----------------------ISYRPL--------------------------------LLRRL 330

  Fly   297 RKDKNLLVIYLITFL----------------------SIWPFAGVDSTAPVYLKTNMGFEYEEVS 339
            .....::::.::|||                      |.|. ||:.....|............::
Yeast   331 VAKPAIIIVNMVTFLLCTGYNGQMIYSVQFFQLIFASSAWK-AGLHLIPIVITNVIAAIASGVIT 394

  Fly   340 MMLGLLSVLAITSNILLGYIMNIVGA----------KWSIRLGLLLL------------------ 376
            ..|||:..|     ::.|.::.::||          ..|.::|:|||
Yeast   395 KKLGLVKPL-----LIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQL 454

  Fly   377 ------------FLQMLFFGFGTHHWMYWLSSILAAL--ATIIPAA-NNAVASIYASP------- 419
                        |:::..|    :.:|..|.:.|..:  .|:..|: :|.|:..:..|
Yeast   455 QITKDRPEAAMDFIEVTAF----NTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPYEGKTVD 515

  Fly   420 ----------DNRGAVLGIISGIECLSEGVGPAFF--------GLLFFIF----------QDDSE 456
                      |...:.:|.|     ||:.:...|:        |.||..|          :||:.
Yeast   516 DMILYRLQNYDGSHSTIGNI-----LSDSIKNVFWMDLGFYALGFLFCSFSSNKKLIIPKKDDTP 575

  Fly   457 TD 458
            .|
Yeast   576 ED 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:475125	101/587 (17%)
VBA5	NP_013031.3	MFS_Azr1_MDR_like	43..493	CDD:341045	84/496 (17%)