Protein Alignment CG17637 and VBA2

DIOPT Version :10

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_009852.3
• Gene: VBA2 / 852596
• SGDID: S000000497
• Length: 474
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 89/518 - (17%)
• Similarity: 171/518 - (33%)
• Gaps: 138/518 - (26%)

  Fly    71 ILGFVTT----------PVMGAISDFHGRKVVMLLA-VATTYAPIPFMMLKSWWFFAILTVSSIC 124
            |..::||          |:.|:.||..||:..:..| .|.|...:.....|:.:..:.:...:..
Yeast     3 ISNWITTAYLITSTSFQPLYGSFSDALGRRNCLFFANGAFTIGCLACGFSKNIYMLSFMRALTGI 67

  Fly   125 GSTYSSSLAYVADTTTVENRSKG--YGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGM 187
            |.....:|:.:.::..:.:..:|  ..|.....|.|.....|.|..:..|.|.....||.....:
Yeast    68 GGGGLITLSTIVNSDVIPSSKRGIFQAFQNLLLGFGAICGASFGGTIASSIGWRWCFLIQVPISV 132

  Fly   188 INILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVNVEVNKPTSQN 252
            |:.:.:.:.||            |:...|            ::........||:..:::...|..
Yeast   133 ISSILMNYYVP------------NQKEYN------------RQNSSIFQNPGKILRDIDVMGSIL 173

  Fly   253 IVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWE------------------VLRKSRKD 299
            |:|...|...:               :..|...|...|.                  :|.:.:..
Yeast   174 IITGLTLQLLY---------------LSLGCSTSKLSWTSPSVLLLLVGSVIILLLFILHERKTS 223

  Fly   300 KNLLV-------IYLITFLSIWPFAGVDS-----TAPVYLKTNMGFEYEEVSMMLGLLSVLAITS 352
            ...::       .|.:..|||....|..|     |.|::.:..:|....:..:.|.:.|:.....
Yeast   224 ARAIIPMELVNSSYSVVVLSISILVGFASYAYLFTLPLFFQIVLGDSTAKAGLRLTIPSLFTPVG 288

  Fly   353 NILLGYIMNIVGAKWS-----IRLGLLLLFLQMLFFGF---GTHHWMYWLSSILAALATII--PA 407
            :::.|:.|    :|::     :.:|:.|:||....|.|   .:.:|:..|..|.|.|...|  |.
Yeast   289 SLITGFSM----SKYNCLRLLLYIGISLMFLGNFLFLFIEKTSPNWLIGLFLIPANLGQGITFPT 349

  Fly   408 ANNAVASIYASPDNRGAV--------LGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSP 464
            .......:::..|...|.        :|.:.|:...:..:..:|.|||    :.:.:..|..|..
Yeast   350 TLFTFIFMFSKSDQATATSTLYLFRSIGSVWGVAISAGVIQLSFAGLL----RSNLKGLLDENKI 410

  Fly   465 ISMPFVISAISVFVA--------IVLSSF----------------------IKKDTLGNEETR 497
            ..:...:||.|.::.        .|:.||                      |.||.|...:||
Yeast   411 KKLIVQLSANSSYIGSLHGEVKNTVIKSFDEATKRAHLMSTLLSSLALILCILKDNLAKPKTR 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:475125	83/506 (16%)
VBA2	NP_009852.3	MFS	1..384	CDD:475125	71/423 (17%)
		TRI12	<107..>249	CDD:115279	25/180 (14%)