Protein Alignment CG17637 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 80/468 - (17%)
• Similarity: 151/468 - (32%)
• Gaps: 181/468 - (38%)

  Fly    50 LSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWF 114
            |:|.||.......|::             .:|::....||:.|.|:.:.
Human   142 LNGLFGGFSAFWSGVM-------------ALGSLGSSEGRRSVRLILID---------------- 177

  Fly   115 FAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVI 179
             .:|.::..|||..|..|               :..:|...|.|:..:..       |...||..
Human   178 -LMLGLAGFCGSMASGHL---------------FKQMAGHSGQGLILTAC-------SVSCASFA 219

  Fly   180 LIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVNVE 244
            |:.::        ::..||||:....:::            ..||.:|           |.|.
Human   220 LLYSL--------LVLKVPESVAKPSQEL------------PAVDTVS-----------GTVG-- 251

  Fly   245 VNKPTSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLIT 309
                 :...:...:||||::.                |...|..      |::..|..:.:..:.
Human   252 -----TYRTLDPDQLDQQYAV----------------GHPPSPG------KAKPHKTTIALLFVG 289

  Fly   310 FLSIWPFA--GVDSTAPVY-LKTNMGFEYEEVS---------MMLGLLSVLAI------TSNILL 356
            .: |:..|  |.....|:: |:..:|:...:|.         .:...|.||..      |:.|::
Human   290 AI-IYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMI 353

  Fly   357 GYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDN 421
            |.:        |...|.|||       .|....:|::::..:...| :||     |.:|
Human   354 GMV--------SFGSGALLL-------AFVKETYMFYIARAVMLFA-LIP-----VTTI------ 391

  Fly   422 RGAVLGIISGIECLSEGVGPAFFGLLFFIFQ-------------DDSETDLKVNSPISMPFVISA 473
            |.|:..:|.|          :.:|.:|.|.|             .:....|.::..:...|.:|:
Human   392 RSAMSKLIKG----------SSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSS 446

  Fly   474 ISVFVAIVLSSFI 486
            ...|:||:..|.:
Human   447 FLSFLAIIPISIV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:119392	80/468 (17%)
		MFS_1	30..441	CDD:284993	69/408 (17%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	73/428 (17%)
		MFS	<282..453	CDD:304372	37/208 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840