Protein Alignment CG17637 and SLC67A1

DIOPT Version :10

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001302430.1
• Gene: SLC67A1 / 5002
• HGNCID: 10964
• Length: 509
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 96/504 - (19%)
• Similarity: 186/504 - (36%)
• Gaps: 149/504 - (29%)

  Fly    18 SGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYG----VRGILGFVTTP 78
            |.:|::||   :::|::  .:...||..|::.....:.:|.|.:|.:.:|    ..|:|..:..|
Human   103 SALGRSSV---ILLTYV--LAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGP 162

  Fly    79 VMGAISDFHGRK------------VVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGS---TY 128
            |.|..:|..|.:            :.:|||.|::.| :|.:.|        |..|.:.|:   |.
Human   163 VFGRFADQRGARAALTLSFLAALALYLLLAAASSPA-LPGVYL--------LFASRLPGALMHTL 218

  Fly   129 SSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFI 193
            .::...:.|.:..|.|....|.:...||.|:.....||..|:.:||.....::|.:..::..:..
Human   219 PAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLS 283

  Fly   194 IFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVNVEVNKPTSQNIVTNKE 258
            ...:|.|                 .:..|.|..:|      |.|..:.:|
Human   284 FTCIPAS-----------------TKGAKTDAQAP------LPGGPRASV--------------- 310

  Fly   259 LDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLV---------IYLITFLSI- 313
                                .|..::.|     :||.....:..||         ::::.|..|
Human   311 --------------------FDLKAIAS-----LLRLPDVPRIFLVKVASNCPTGLFMVMFSIIS 350

  Fly   314 WPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNILLGYIMNIVGAKWSIRLGLLLLFL 378
            ..|..:::....||   |.|        .|||.:  :|..:::|.:.:....:..:|..:|:..:
Human   351 MDFFQLEAAQAGYL---MSF--------FGLLQM--VTQGLVIGQLSSHFSEEVLLRASVLVFIV 402

  Fly   379 QMLFFGFGTHHWMYWLSSI----------LAALATIIPAANNAVASIYASPDNRGAVLGIISGIE 433
            ..|.        |.|:||:          :.:|.|:....::.:....::.|. |.:||:.:.::
Human   403 VGLA--------MAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDT-GTMLGLCASVQ 458

  Fly   434 CLSEGVGPAFFGLLFFIFQDDSETDLKVNSPISMPFVISAISVFVAIVL 482
            .|...:||...|||:..|          ..|: ...|..||:..|.:||
Human   459 PLLRTLGPTVGGLLYRSF----------GVPV-FGHVQVAINTLVLLVL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:475125	93/497 (19%)
SLC67A1	NP_001302430.1	MFS_SLC22A18	110..498	CDD:340889	93/497 (19%)