DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17637 and mfsd14a1

DIOPT Version :9

Sequence 1:	NP_649237.1	Gene:	CG17637 / 40275	FlyBaseID:	FBgn0037004	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_998692.2	Gene:	mfsd14a1 / 406848	ZFINID:	ZDB-GENE-040426-2935	Length:	485	Species:	Danio rerio

Alignment Length:	519	Identity:	176/519 - (33%)
Similarity:	259/519 - (49%)	Gaps:	109/519 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAQLKFLRPLVKVLVNRS----------------GIGKASVWHAVIVTFMHYFSWGLLTVPFIEK 49
            |.|.|      |..||||                |.|..||:|||||.|:.:|:|||||.|.:..
Zfish     1 MTQKK------KKRVNRSLLLAKKIIIKDGGTPQGFGSPSVYHAVIVIFLEFFAWGLLTAPTLGA 59

  Fly    50 LSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWF 114
            |..:|.....|::||:.||:|:|.|::.|::||:||..|||..:||.|..|.||||.|.:..||:
Zfish    60 LDETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWY 124

  Fly   115 FAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVI 179
            ||:::||.:...|:|...|||||.|....||..||.|:|:|.|.:..||::|.||...||...|:
Zfish   125 FAMISVSGVFAVTFSVIFAYVADITQEHERSMAYGMVSATFAASLVISPAIGAYLSHVYGDTLVV 189

  Fly   180 LIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVNVE 244
            ::|:...|::|.||:.||||||                                         .|
Zfish   190 VLASAIAMLDICFILVAVPESL-----------------------------------------PE 213

  Fly   245 VNKPTSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLIT 309
            ..:|.|.....:.|                           .:|.:..|||..:|..:|:|.:..
Zfish   214 KMRPASWGAPISWE---------------------------QADPFASLRKVGQDSTVLLICITV 251

  Fly   310 FLSIWPFAGVDSTAPVYLKTNMGFEYEEVS---MMLGLLSVLAITSNILLGYIMNIVGAKWSIRL 371
            |||..|.||.:|:..:||:..|||..|.|:   .:||||||:|.|  ::|..:|..:|.|.:|.|
Zfish   252 FLSYLPEAGQNSSFFLYLQQIMGFSSESVAAFIAVLGLLSVVAQT--VVLSLLMRSIGNKNTILL 314

  Fly   372 GLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLS 436
            ||....||:.::|||:..||.|.:..:||:::|...|.:|:.|..|.||.:|...|:::||..|.
Zfish   315 GLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALISRTADPDQQGVGQGMVTGIRGLC 379

  Fly   437 EGVGPAFFGLLFFIFQDDSE------------TDLKVNSPI--SMPFVISAISVFVAIVLSSFI 486
            .|:|||.:|.:|:||..:.:            .||...|.|  ..||:..|.||.:|::::.||
Zfish   380 NGLGPALYGFIFYIFHVELDKVPEKGPDVQHHRDLHQQSAIIPGPPFLFGACSVLLALLVALFI 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:119392	165/479 (34%)
CG17637	NP_649237.1	MFS_1	30..441	CDD:284993	142/413 (34%)
mfsd14a1	NP_998692.2	MFS	38..395	CDD:119392	150/426 (35%)
mfsd14a1	NP_998692.2	MFS_1	40..384	CDD:284993	142/413 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53596
OrthoDB	1	1.010	-	-		D139531at33208
OrthoFinder	1	1.000	-	-		FOG0001490
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23504
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.820