DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17637 and Mfsd14b

DIOPT Version :10

Sequence 1:NP_649237.1 Gene:CG17637 / 40275 FlyBaseID:FBgn0037004 Length:504 Species:Drosophila melanogaster
Sequence 2:NP_001100804.1 Gene:Mfsd14b / 306687 RGDID:1308377 Length:507 Species:Rattus norvegicus


Alignment Length:487 Identity:157/487 - (32%)
Similarity:243/487 - (49%) Gaps:95/487 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 GIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAI 83
            |.|:.||:||..|.|..:|:|||||.|.:..|..:|.....|::||:.||:|:|.|::.|::||:
  Rat    41 GFGQPSVYHAAFVIFFEFFAWGLLTTPMLTVLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGAL 105

  Fly    84 SDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGY 148
            ||..|||..:|..|..|..|||.|.:..||:|.:::||.:...|:|...|||||.|....||..|
  Rat   106 SDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFGMISVSGVFSVTFSVIFAYVADFTQEHERSTAY 170

  Fly   149 GFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNEN 213
            |:|:|:|.|.:..||::|.||..:||.:.|:|:||:..:::|.||:.||||||            
  Rat   171 GWVSATFAASLVSSPAIGTYLSSNYGDSLVVLVATVVALLDICFILVAVPESL------------ 223

  Fly   214 NDNKVEDTKVDDISPKEKKENLNGEGKVNVEVNKPTSQNIVTNKELDQQFSKEENLQNDLTEKEK 278
                                                                          .||
  Rat   224 --------------------------------------------------------------PEK 226

  Fly   279 IDNGSLNSSDLWE------VLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEE 337
            |...|..:...|:      .|:|..||..:|:|.:..|||..|.||..|:..:||:..:||...:
  Rat   227 IRPASWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVK 291

  Fly   338 V---SMMLGLLSVLAITSNILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILA 399
            :   ..|:|:||:||.|  :.|..:|..:|.|.::.|||....||:.::|||...||.|.:..:|
  Rat   292 IVAFIAMVGILSILAQT--VFLSKLMRSLGNKNTVLLGLGFQILQLAWYGFGAQAWMMWAAGTVA 354

  Fly   400 ALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDD-SETDLKV-- 461
            |:::|...|.:|:.|..|..|.:|...|||:||..|..|:|||.:|.:|::|..: :|...|:  
  Rat   355 AMSSITFPAVSALISRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYLFHVELNELGPKLDS 419

  Fly   462 -NSPI------SMPFVISAISVFVAIVLSSFI 486
             |.|:      ..||:..|..|.::.:::.||
  Rat   420 DNDPLQGAFIPGPPFLFGACIVLMSFLVALFI 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17637NP_649237.1 MFS 25..487 CDD:475125 154/481 (32%)
Mfsd14bNP_001100804.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
MFS_MFSD14 47..452 CDD:340945 154/481 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 462..483
Blue background indicates that the domain is not in the aligned region.

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