Protein Alignment CG17637 and SLC46A3

DIOPT Version :9

• Sequence 1: NP_649237.1
• Gene: CG17637 / 40275
• FlyBaseID: FBgn0037004
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001129391.1
• Gene: SLC46A3 / 283537
• HGNCID: 27501
• Length: 463
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 82/414 - (19%)
• Similarity: 152/414 - (36%)
• Gaps: 109/414 - (26%)

  Fly    47 IEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLL----AVATT------- 100
            ::|....| |..:.:.||      |.|.|:|.::.:|||.:|||..|:|    |:||:
Human    65 VQKKVSRF-NLQMDISGL------IPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLC 122

  Fly   101 YAPIPFMMLKSWWFFAILTVSSICG---STYSSSLAYVADTTTVENRSKGYGFVAASFGAGI--A 160
            |...||.:|     .|...:.:.||   :.:.:..||:.|... |::.|........|..|:  .
Human   123 YFAFPFQLL-----IASTFIGAFCGNYTTFWGACFAYIVDQCK-EHKQKTIRIAIIDFLLGLVTG 181

  Fly   161 FSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDD 225
            .:.....|.::..|.....||..::..:|:::|:|.:.:
Human   182 LTGLSSGYFIRELGFEWSFLIIAVSLAVNLIYILFFLGD-------------------------- 220

  Fly   226 ISPKEKKENLNGEGKVNVEVNKPTSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLW 290
                              .|.:.:|||:.        .|..|..:|.....
Human   221 ------------------PVKECSSQNVT--------MSCSEGFKNLFYRT-------------- 245

  Fly   291 EVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYL--KTNMGFEYEEVSMMLG--LLSVLAIT 351
            .:|.|:...|...::.|:.|..|..|..|...||:::  :.:....:.||.:..|  |.|...:|
Human   246 YMLFKNASGKRRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALGSASFLT 310

  Fly   352 SNI---LLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIP--AANNA 411
            |.:   |..|.|..:...:   :|:......|....|.:...|.:|:.: ..|.||:|  ...:.
Human   311 SFLGIWLFSYCMEDIHMAF---IGIFTTMTGMAMTAFASTTLMMFLARV-PFLFTIVPFSVLRSM 371

  Fly   412 VASIYASPDNRGAVLGIISGIECL 435
            ::.:..|.: :|.:...|:.:|.|
Human   372 LSKVVRSTE-QGTLFACIAFLETL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17637	NP_649237.1	MFS	25..487	CDD:119392	82/414 (20%)
		MFS_1	30..441	CDD:284993	82/414 (20%)
SLC46A3	NP_001129391.1	MFS_1	81..399	CDD:311564	78/397 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840