DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18281 and YJL163C

DIOPT Version :9

Sequence 1:	NP_649236.1	Gene:	CG18281 / 40274	FlyBaseID:	FBgn0037003	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_012372.1	Gene:	YJL163C / 853276	SGDID:	S000003699	Length:	555	Species:	Saccharomyces cerevisiae

Alignment Length:	525	Identity:	104/525 - (19%)
Similarity:	199/525 - (37%)	Gaps:	137/525 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVR--GILG 73
            |:.:|  |.|..:::..|..::......||        :||...|.  :.|...:.|:|  |:|.
Yeast   123 VQTIV--SSISSSTMMIAGAISIFMAGKWG--------ELSDRIGR--VRVFKYMSGIRVIGLLT 175

  Fly    74 FVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADT 138
            .|.|  :.:...:|...:|:...:..::..:          ||::          ::..:||:|.
Yeast   176 HVFT--LSSKMKYHKWAIVLTACIVPSFGGL----------FALV----------ANGNSYVSDI 218

  Fly   139 TTVENRSKGYGIVAASFGAGIAFSPSLGNYLMK-SYGSASVILIAAITGLINIMFIIFAVPESLV 202
            ...|:|....||:.:...|.:...|..|::|:| ::|:..:.:..:|.      |:|.|    |:
Yeast   219 VKTEHRMVTIGIMMSCIYATMGVGPMFGSFLVKWTHGNGFIPIYTSIA------FVILA----LI 273

  Fly   203 LKEKNNMLDEESDNKMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEE 267
            :.| ..|::...:.:|    ...:.....|.|||       :|..|:
Yeast   274 ICE-TIMVEPRHETQM----AHSQSTYTKRREKL-------RSQSGS------------------ 308

  Fly   268 NLQNDLTEKEKIDNGSLNSSDLWEVLRKSRK------DKNLLV----IYLITFLSIWPFAGVDST 322
               :|....:.:..|......|.::|...:|      ....||    :.|:..|.|....|..|.
Yeast   309 ---DDARNYQSVTYGKFQIMRLMDLLAPVKKLWLKPDSAGSLVPRHTVILLIVLDILFVCGTTSC 370

  Fly   323 APVYLKTNMGFEYE----EVSMMLGLLSV------LAITSNLL---------LGYIINIVGAKWS 368
            .|..:..:. :||:    |:...:.:|.:      |.::..||         |.:.|:.:.. :.
Yeast   371 MPALILFST-YEYKWHAVELGYFISILGIGRGVVLLVVSPTLLYTLKRIYQHLNHSIDKIDI-FC 433

  Fly   369 IRLGLLLLLLQLFF---FGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIIS 430
            |:..::::.|.||.   ||..|...|...:.:.|..|...|...:.:.. |.|..:.|.:.|.::
Yeast   434 IQFSMIVITLSLFVMIRFGEKTPTSMIIFALLQALSAFCSPTLQSGIIK-YTSKKHTGEMFGAMA 497

  Fly   431 GI-ECLSEGVGPAFFGVLFFIFQDDSKNKVNSPISM--PFVISAIGVFVAIVLTGFIKKETVEKA 492
            .: .|:...:.|    :|..::  .|...||..:.|  ||..|    .|||:||.|::
Yeast   498 LVRSCVMLVIPP----ILLKLY--GSTVSVNPSLFMYIPFSTS----IVAILLTFFLR------- 545

  Fly   493 PLIYK 497
              |||
Yeast   546 --IYK 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:119392	97/497 (20%)
CG18281	NP_649236.1	MFS_1	30..441	CDD:284993	81/446 (18%)
YJL163C	NP_012372.1	MFS	139..545	CDD:421695	96/493 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810