DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18281 and AT2G16990

DIOPT Version :9

Sequence 1:	NP_649236.1	Gene:	CG18281 / 40274	FlyBaseID:	FBgn0037003	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001031360.1	Gene:	AT2G16990 / 816202	AraportID:	AT2G16990	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	117/517 - (22%)
Similarity:	215/517 - (41%)	Gaps:	92/517 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GIGKASVWHAVIVTFMHYFSWGLLTVPFIEKL------SGSFGNRVLLV--DGLVYGVRGILGFV 75
            |||  .:.|.:...|:..|: |.:.||.|..:      ||...:..|.|  .|......|:...:
plant     4 GIG--GLRHMLATVFLSAFA-GFMVVPVITDVTVAAVCSGPDDSCSLAVYLTGFQQVAIGMGTMI 65

  Fly    76 TTPVMGAISDFHGRKVVMLLAVATTYAPIPFMM-----LKSWWFFAI--LTVSSIC-GSTYSSSL 132
            ..||:|.:||.:|.|.::.|.:..:..| |.::     :|.::.|.|  :..|.:| |:....:.
plant    66 MMPVIGNLSDRYGIKTILTLPMCLSIVP-PVILGYRRDIKFFYVFYISKILTSMVCEGTVDCLAY 129

  Fly   133 AYVADTTTVENRSKGYGI------VAASFGAGIA-FSPSLGNYLMKSYGSASVILIAAITGLINI 190
            ||||.......|...:||      :|..||..:| |.|           .|....::||:..:.:
plant   130 AYVAVNIHGSTRISAFGILAGIKTIAGLFGTLVARFLP-----------IALTFQVSAISFFVGL 183

  Fly   191 MFIIFAVPESLVLKEKNNMLDEESDNKMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVT 255
            :::      .:.||||.|  |:|.|:.                    :|.:.::.:|.:....:.
plant   184 VYM------RVFLKEKLN--DDEDDDL--------------------HHGTYHQEDHDSINTTML 220

  Fly   256 NKELGQQFNKEENLQNDLTEKEKIDNGSLNS-SDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGV 319
                      .|.:.||...|.::.:...:| .|:..:::.|......||   :||.|.:..:|:
plant   221 ----------AEPILNDRPIKTQVFHKKYSSLKDMISLMKTSTIFFQALV---VTFFSSFSDSGM 272

  Fly   320 DSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNL-LLGYIINIVGAKWSIRLGLLLLLLQLFFF 383
            :|....:||...||:.::.:.:|.|::::...|.| :|....:.:|....:..||.:..:.:...
plant   273 ESAFLYFLKARFGFDKKQFADLLLLITIVGSISQLFVLPRFASAIGECKLLSTGLFMEFINMAIV 337

  Fly   384 GFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLF 448
            ......|:.:|:::....|..:..:...:||....|..:|.|.|.|||:....:.|.|..|..|.
plant   338 SISWAPWVPYLTTVFVPGALFVMPSVCGIASRQVGPGEQGKVQGCISGVRSFGKVVAPFVFSPLT 402

  Fly   449 FIFQDDSKNKVNSPISMP-FVISAIGVFVAIVLTGFIKKETVEKAPL--IYKIIDDASEDEV 507
            .:|.  ||   |:|...| |.:..|.:   ..|.||.:...::..|.  :.|.|:..|.:||
plant   403 ALFL--SK---NAPFYFPGFSLLCISL---SSLIGFFQSLLIKDVPTPPLNKAINKTSGEEV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:119392	108/485 (22%)
CG18281	NP_649236.1	MFS_1	30..441	CDD:284993	93/435 (21%)
AT2G16990	NP_001031360.1	MFS	11..417	CDD:119392	102/464 (22%)
AT2G16990	NP_001031360.1	MFS_1	11..395	CDD:284993	93/437 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I2229
OMA	1	1.010	-	-		QHG53596
OrthoDB	1	1.010	-	-		D582396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1054
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23504
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980