Protein Alignment CG18281 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_649236.1
• Gene: CG18281 / 40274
• FlyBaseID: FBgn0037003
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 76/418 - (18%)
• Similarity: 138/418 - (33%)
• Gaps: 139/418 - (33%)

  Fly    50 LSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWF 114
            |:|.||.......|::             .:|::....||:.|.|:.:.
Human   142 LNGLFGGFSAFWSGVM-------------ALGSLGSSEGRRSVRLILID---------------- 177

  Fly   115 FAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVI 179
             .:|.::..|||..|..|               :..:|...|.|:..:..       |...||..
Human   178 -LMLGLAGFCGSMASGHL---------------FKQMAGHSGQGLILTAC-------SVSCASFA 219

  Fly   180 LIAAITGLINIMFIIFAVPESLVLKEKNNM--LDEESD--NKMEDINPKERKEILNREEKLNNHV 240
            |:.::        ::..|||| |.|....:  :|..|.  .....::|.:    |:::..:.:..
Human   220 LLYSL--------LVLKVPES-VAKPSQELPAVDTVSGTVGTYRTLDPDQ----LDQQYAVGHPP 271

  Fly   241 SANKSN-HGTSQNL----------------------VTNKELGQQFNKEENLQNDLTEKEKIDNG 282
            |..|:. |.|:..|                      |..:.||  :|:.:           :..|
Human   272 SPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLG--WNQVQ-----------VGYG 323

  Fly   283 -----SLNSSDLWEVLRKSR--KDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSM 340
                 ::..:....||..||  :|..:::|.:::|       |..:....::|....|......|
Human   324 MAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSF-------GSGALLLAFVKETYMFYIARAVM 381

  Fly   341 MLGLLSVLAITSNL--------------LLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWM 391
            :..|:.|..|.|.:              :|...:.:.|...|.....:..|....|.|.     .
Human   382 LFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGS-----C 441

  Fly   392 YWLSSILAALATIIPAANNAVASIYASP 419
            :.|||.|:.|| |||.:..|...:..||
Human   442 FALSSFLSFLA-IIPISIVAYKQVPLSP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:119392	76/418 (18%)
		MFS_1	30..441	CDD:284993	76/418 (18%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	60/363 (17%)
		MFS	<282..453	CDD:304372	33/196 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810