Protein Alignment CG18281 and SLC67A1

DIOPT Version :10

• Sequence 1: NP_649236.1
• Gene: CG18281 / 40274
• FlyBaseID: FBgn0037003
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001302430.1
• Gene: SLC67A1 / 5002
• HGNCID: 10964
• Length: 509
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 91/492 - (18%)
• Similarity: 177/492 - (35%)
• Gaps: 127/492 - (25%)

  Fly    18 SGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYG----VRGILGFVTTP 78
            |.:|::||   :::|::  .:...||..|::.....:.:|.|.:|.:.:|    ..|:|..:..|
Human   103 SALGRSSV---ILLTYV--LAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGP 162

  Fly    79 VMGAISDFHGRK------------VVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGS---TY 128
            |.|..:|..|.:            :.:|||.|::.| :|.:.|        |..|.:.|:   |.
Human   163 VFGRFADQRGARAALTLSFLAALALYLLLAAASSPA-LPGVYL--------LFASRLPGALMHTL 218

  Fly   129 SSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFI 193
            .::...:.|.:..|.|....|.:...||.|:.....||..|:.:||.....::||:..|:..:..
Human   219 PAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLS 283

  Fly   194 IFAVPESLVLKEKNNMLDEESDNKMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKE 258
            ...:|.|....:.:.........:....:.|....:|...:.....:....||..|...:|....
Human   284 FTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSI 348

  Fly   259 LGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTA 323
            :...|.:.|..|..                                 ||::|
Human   349 ISMDFFQLEAAQAG---------------------------------YLMSF------------- 367

  Fly   324 PVYLKTNMGFEYEEVSMMLGLLSVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTH 388
                              .|||.:  :|..|::|.:.:....:..:|..:|:.::    .|..
Human   368 ------------------FGLLQM--VTQGLVIGQLSSHFSEEVLLRASVLVFIV----VGLA-- 406

  Fly   389 HWMYWLSSI----------LAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAF 443
              |.|:||:          :.:|.|:....::.:....::.|. |.:||:.:.::.|...:||..
Human   407 --MAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDT-GTMLGLCASVQPLLRTLGPTV 468

  Fly   444 FGVLFFIFQDDSKNKVNSPISMPFVISAIGVFVAIVL 480
            .|:|:..|        ..|: ...|..||...|.:||
Human   469 GGLLYRSF--------GVPV-FGHVQVAINTLVLLVL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:475125	88/485 (18%)
		235kDa-fam	<203..>299	CDD:130673	9/95 (9%)
SLC67A1	NP_001302430.1	MFS_SLC22A18	110..498	CDD:340889	88/485 (18%)