Protein Alignment CG18281 and Slc46a2

DIOPT Version :10

• Sequence 1: NP_649236.1
• Gene: CG18281 / 40274
• FlyBaseID: FBgn0037003
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_066395.3
• Gene: Slc46a2 / 30936
• MGIID: 1353616
• Length: 479
• Species: Mus musculus
• Alignment Length: 487
• Identity: 91/487 - (18%)
• Similarity: 175/487 - (35%)
• Gaps: 157/487 - (32%)

  Fly    64 LVYGVRGILGFVTTPVMGA-----ISDFHGRKVVMLLAVATTYAPIPFMMLK---SW---WFFAI 117
            ::|.:  :||.  ||::.|     :||.:.||:.:..|:.........::||   .|   ..:..
Mouse    81 IIYNL--VLGL--TPLLSAYGLGWLSDRYHRKISICTAMLGFLLSRIGLLLKVMLDWPVEVMYGA 141

  Fly   118 LTVSSICG--STYSSSLAYVADTTTVENRSKGYGIVAASFGAGIA-FSPSLGN-YLMK---SYGS 175
            ..::.:||  |.|.|.:..:......|.| :...::......|:| ||.|:.: :|.|   .:.:
Mouse   142 AALNGLCGSFSAYWSGVMALGSLGCSEGR-RSVRLILIDLVLGLAGFSGSMASGHLFKQIVGHSA 205

  Fly   176 ASVILIAAITG-----LINIMFIIFAVPESLVLKEKNNMLDEESDNKMEDINPKERKEILNREEK 235
            ..::|.|...|     |...:|:: .||||                               :..|
Mouse   206 QGLLLTACSVGCAAFALFYSLFVL-KVPES-------------------------------KPNK 238

  Fly   236 LNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDK 300
            ::..|.......||.:.|..:::     :|:...:|..|.                  .|.:..:
Mouse   239 VHPTVDTVSGMMGTYRTLDPDQQ-----DKQNVPRNPRTP------------------GKGKSSQ 280

  Fly   301 NLLVIYLITFLSIWPFAG---VDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNLLLGYIINI 362
            ..:|..|.....|:..|.   ||..|...||..:  .:.:|.:..|:.|          ||||.|
Mouse   281 REVVALLFVGAIIYDLAAVGTVDVMALFVLKEPL--HWNQVQLGYGMAS----------GYIIFI 333

  Fly   363 VGAKWSIRLGLL----------LLLLQLFFFGFGT-------HHWMYWLSSILAALATIIPAANN 410
            ...     ||:|          ::::.:..||.|.       ..:|::::..:...| :||
Mouse   334 TSF-----LGVLVFSRCFRDTTMIIIGMLSFGSGALLLAFVKETYMFYIARAIMLFA-LIP---- 388

  Fly   411 AVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQ----------DDSKNKV-----N 460
             :.:|.::                :|:.:..:.:|.:|.|.|          ....||:     :
Mouse   389 -ITTIRSA----------------MSKLIKDSSYGKIFVILQLCLTLTGVVTSTIYNKIYQLTLD 436

  Fly   461 SPISMPFVISAIGVFVAIVLTGFIKKETVEKA 492
            ..|...||:|:...|:|||..|.:..:.|.::
Mouse   437 KFIGTCFVLSSFLSFLAIVPIGVVAYKQVPRS 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:475125	90/478 (19%)
		235kDa-fam	<203..>299	CDD:130673	9/95 (9%)
Slc46a2	NP_066395.3	MFS_SLC46A2_TSCOT	19..461	CDD:341008	90/478 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..277		5/44 (11%)