DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18281 and Slc46a2

DIOPT Version :9

Sequence 1:	NP_649236.1	Gene:	CG18281 / 40274	FlyBaseID:	FBgn0037003	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001100122.1	Gene:	Slc46a2 / 298034	RGDID:	1310485	Length:	480	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	85/486 - (17%)
Similarity:	167/486 - (34%)	Gaps:	160/486 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 LVYG-VRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLK---SW---WFFAILTVS 121
            ::|. |.|:...::..|:|.:||.:.||:.:..|:.........::||   .|   ..:....::
  Rat    81 IIYNLVVGLTPLLSAYVLGWLSDRYHRKISICTAMLGFLLSRIGLLLKVMLDWPLEVMYGAAALN 145

  Fly   122 SICG--STYSSSLAYVADTTTVENRSK----------GYGIVAASFGAGIAFSPSLGNYLMKSYG 174
            .:||  |.|.|.:..:...:..::|..          |......|..:|..|...:|:
  Rat   146 GLCGGFSAYWSGVMALGSLSCSQSRRSVRLILIDLVLGLAGFCGSMASGHLFKQIVGH------- 203

  Fly   175 SASVILIAAIT------GLINIMFIIFAVPESLVLKEKNNMLDEESDNKMEDINPKERKEILNRE 233
            ||..:|:.|.:      .|...:|:: .|||:                             :::.
  Rat   204 SAQGLLLTACSVGCAAFALFYSLFVL-KVPEA-----------------------------VSKP 238

  Fly   234 EKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRK 298
            .|::..|.......||.:.|..:::      .:.|:|.:.....|                  .|
  Rat   239 NKVHPTVDTVSGMMGTYRTLDPDQQ------DKPNIQANPPTPGK------------------EK 279

  Fly   299 DKNLLVIYLITFLSIWPFAGV---DSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSNLLLGYII 360
            ....::..|.....::..|.|   |..|...||..:  .:.:|.:..|:.|          ||||
  Rat   280 PSQAIIALLFVGAIVYDLAVVGTLDVMALFVLKDPL--HWNQVQLGYGMAS----------GYII 332

  Fly   361 NIVGAKWSIRLGLL----------LLLLQLFFFGFGT-------HHWMYWLSSILAALATIIPAA 408
            .|...     ||:|          ::::.:..||.|.       ..:|::::..:...| :||
  Rat   333 FITSF-----LGVLVFSRYFRDTTMIIIGMVSFGSGALLLAFVKKTYMFYIARAVMLFA-LIP-- 389

  Fly   409 NNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQ----------DDSKNKV---- 459
               :.:|.::                :|:.|..:.:|.:|.|.|          ....||:
  Rat   390 ---ITTIRSA----------------MSKLVKDSSYGKIFVILQLCLALTGVVTSTMYNKIYQLT 435

  Fly   460 -NSPISMPFVISAIGVFVAIVLTGFIKKETV 489
             |......|::|:...|:|||..|.:..:.|
  Rat   436 LNKFAGTCFLLSSFLSFLAIVPIGVVAYKQV 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:119392	84/480 (18%)
CG18281	NP_649236.1	MFS_1	30..441	CDD:284993	70/421 (17%)
Slc46a2	NP_001100122.1	MFS	86..433	CDD:119392	75/446 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810