Protein Alignment CG18281 and T25D3.4

DIOPT Version :10

• Sequence 1: NP_649236.1
• Gene: CG18281 / 40274
• FlyBaseID: FBgn0037003
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_493670.2
• Gene: T25D3.4 / 188895
• WormBaseID: WBGene00020798
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 501
• Identity: 162/501 - (32%)
• Similarity: 252/501 - (50%)
• Gaps: 105/501 - (20%)

  Fly    22 KASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDF 86
            :|||.||::|.|:.||:|||||||.|..|:.:|.....|::|||.||:|:|.|::.|::||:||.
 Worm    72 EASVSHALVVIFLEYFAWGLLTVPVINVLAETFPTNKFLMNGLVLGVKGLLSFLSAPLVGALSDV 136

  Fly    87 HGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIV 151
            .|||..::|.|..|..|||.:.:..||:|::.::|.:...|:|..||||||.|....||..||:|
 Worm   137 WGRKAFLILTVLCTCMPIPCLKISPWWYFSLFSLSGLFSVTFSVILAYVADITDKSERSSAYGLV 201

  Fly   152 AASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN 216
            :|:|.|.:..||:||.|:.:.||.:.|:|:|.|..:.:::||:..|||||
 Worm   202 SATFAASLVTSPALGAYISEVYGDSLVVLLATIVSVADVIFIVLFVPESL--------------- 251

  Fly   217 KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDN 281
                  |..|                   |.|:...:..|:....|
 Worm   252 ------PSRR-------------------NTGSVSQITPNEVFNWQ------------------- 272

  Fly   282 GSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLS 346
                |:|.:..||...:||.:|.:..|.|||..|.:|..|...||||..:||..|.|:|.:||:.
 Worm   273 ----SADPFGSLRIVWEDKLVLQLATIVFLSYLPESGQFSCFFVYLKLVVGFSPEAVAMYIGLVG 333

  Fly   347 VLAITSNL-LLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALATIIPAANN 410
            :|::.:.. .|..:.:..|.|.:|.|||:..|:||.::|.||.:||.|.:.:|||:::|...:.:
 Worm   334 ILSVVAQTGFLHCLTSRFGTKHTITLGLIFQLIQLTWYGLGTQYWMMWSAGVLAAMSSITYPSIS 398

  Fly   411 AVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQ---DDSKN--------------- 457
            |..||.:..|.:|.|.|:|:||..|..|.|||.||.:|::|.   :|.|:
 Worm   399 AFVSILSDKDKQGTVQGVITGIRGLCTGFGPALFGTVFYLFDVDLEDEKSTGGALSLVAPRKIPE 463

  Fly   458 KVNSPI-----------------------SMPFVISAIGVFVAIVL 480
            |:.:|.                       ..||:|.|:.|..|:::
 Worm   464 KILAPTRNESSWIQQQVDRAAAFDWQFIPGPPFLIGAMMVLFALLI 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:475125	160/498 (32%)
		235kDa-fam	<203..>299	CDD:130673	10/95 (11%)
T25D3.4	NP_493670.2	MFS_MFSD14	75..514	CDD:340945	160/498 (32%)