Protein Alignment CG18281 and Mfsd14a

DIOPT Version :10

• Sequence 1: NP_649236.1
• Gene: CG18281 / 40274
• FlyBaseID: FBgn0037003
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001316129.1
• Gene: Mfsd14a / 103689987
• RGDID: 9294064
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 166/498 - (33%)
• Similarity: 251/498 - (50%)
• Gaps: 104/498 - (20%)

  Fly    19 GIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAI 83
            |||..||:|||||.|:.:|:|||||.|.:..|..:|.....|::||:.||:|:|.|::.|::||:
  Rat    31 GIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGAL 95

  Fly    84 SDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGY 148
            ||..|||..:||.|..|.||||.|.:..||:||:::||.:...|:|...|||||.|....||..|
  Rat    96 SDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAY 160

  Fly   149 GIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEE 213
            |:|:|:|.|.:..||::|.||.:.||.:.|:::|....|::|.||:.||||||
  Rat   161 GLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESL------------ 213

  Fly   214 SDNKMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEK 278
                                                                          .||
  Rat   214 --------------------------------------------------------------PEK 216

  Fly   279 IDNGSLNSSDLWE------VLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEE 337
            :...|..:...||      .|:|..:|..:|:|.:..|||..|.||..|:..:||:..|.|..|.
  Rat   217 MRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPES 281

  Fly   338 VS---MMLGLLSVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILA 399
            |:   .:||:||::|.|  ::|..::..:|.|.:|.|||...:|||.::|||:..||.|.:..:|
  Rat   282 VAAFIAVLGILSIIAQT--IVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVA 344

  Fly   400 ALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN------- 457
            |:::|...|.:|:.|..|..|.:|.|.|:|:||..|..|:|||.:|.:|:||..:.|.
  Rat   345 AMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGPD 409

  Fly   458 -----------KVNSPI-SMPFVISAIGVFVAIVLTGFIKKET 488
                       :.||.| ..||:..|..|.:|:::..||.:.|
  Rat   410 LGTNTSPQHHFEQNSIIPGPPFLFGACSVLLALLVALFIPEHT 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18281	NP_649236.1	MFS	25..485	CDD:475125	160/487 (33%)
		235kDa-fam	<203..>299	CDD:130673	7/101 (7%)
Mfsd14a	NP_001316129.1	MFS_MFSD14	37..449	CDD:340945	160/487 (33%)