DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32425 and C2cd3

DIOPT Version :9

Sequence 1:NP_730546.1 Gene:CG32425 / 40273 FlyBaseID:FBgn0052425 Length:759 Species:Drosophila melanogaster
Sequence 2:NP_001017985.2 Gene:C2cd3 / 277939 MGIID:2142166 Length:2323 Species:Mus musculus


Alignment Length:388 Identity:81/388 - (20%)
Similarity:148/388 - (38%) Gaps:104/388 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   161 WW---------------REPGTCLNEMLGMGRLELRELYRASLLEQCKCIAIRRRD--VHLGSVY 208
            ||               ::|     |::|...|.||.:.::.||.....:.:::.:  ..||.:.
Mouse   621 WWDSNLIFQIYAKKTPQKKP-----EVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLK 680

  Fly   209 LKISLL----------QNLNGSPEQ-------------PQQQQQQPGQKN-ESGNKAAVNCNSKA 249
            :.:.|:          ..|:.|.:.             |:..|.....:| :|.||.......|.
Mouse   681 VTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTRNPQSSNKIHEETTKKT 745

  Fly   250 --VLTPPQPPAPPPPPPQANNNS--KAILECINFMAETNKVRLLRGYL-------------YAGE 297
              ::.|.|..|    ...|:|:|  .|:..| |.:.:.|......|.|             ..||
Mouse   746 QNLVLPDQESA----NSVASNSSIFMAVPSC-NLVHQINGSNKESGLLLHVLLMVPDGKDFVFGE 805

  Fly   298 LRQLTAGGSKTACQELSLEPF------W-QPQPLLSKLTDGGSFELQEQFAIINDERFLQSVERQ 355
            ..:..:......|:..|.|..      | ..||:         |...:...:....:.|:.::..
Mouse   806 REKQPSCNVYLNCKLFSTEEVTRSVVSWGTAQPV---------FNFSQVIPVSLTSKCLERLKNN 861

  Fly   356 QLVME----LRPLG-----GVVRLPLHQFFIAYRDSSITNHLCKGKLPVISIDGWAPIVSAENKT 411
            .:::|    :|..|     |:|:||||||:::::|..|:..|...:.||:::|.:.|::...:..
Mouse   862 VMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGH 926

  Fly   412 PLGELKVLLAIGSESQIAQLKQLRGFDHDNNQVPAPSRTTDLLDMLQNAIAAPTPNIAGPVMP 474
            ..|.|:|.||:||.:||..|::|:  :.:....|...|....||.         |.:|...||
Mouse   927 QNGSLRVFLAMGSSAQIMMLQRLK--NEEGTLPPFSPRPAHFLDQ---------PPVASVAMP 978

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32425NP_730546.1 None
C2cd3NP_001017985.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..27
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..215
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 402..426
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 444..509
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 537..556
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 698..745 8/46 (17%)
C2_C2cd3 1183..1325 CDD:176065
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1550..1599
C2 <1660..1728 CDD:175973
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1798..1824
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1891..1918
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1952..2013
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2074..2163
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2182..2231
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2261..2323
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167844872
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_2CMSF
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0007278
OrthoInspector 1 1.000 - - oto93887
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5564
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
65.820

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