DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-39 and ndufa9

DIOPT Version :9

Sequence 1:	NP_001262116.1	Gene:	ND-39 / 40272	FlyBaseID:	FBgn0037001	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001011432.1	Gene:	ndufa9 / 496917	XenbaseID:	XB-GENE-949551	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	153/351 - (43%)
Similarity:	232/351 - (66%)	Gaps:	24/351 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 AAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKVTGDLGQV 113
            |.:..|..|||:.:|:|||||||:||:||||.|:||:.|:|:|:|||.|..|::.|:..|||||:
Frog    39 AVIPHGKPGRSAVSGVVATVFGASGFLGRYVVNRLGRIGSQVIIPYRCDPYDIMYLRPMGDLGQL 103

  Fly   114 LFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIAREAGVERLIHLS 178
            :|..::.:|..:||.|:::|||||||:|:::|||||.::||.||....:|.:|||||||:.||:|
Frog   104 IFMDWDSKDKDTIRKALQNSNVVINLIGKEWETKNFSYEDVFVNIPRDLALLAREAGVEKFIHMS 168

  Fly   179 SLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGSEDRFLRYYAHIWRRQFR 243
            .||.:       :|..|::|::|..||..||:|||:|.|::|::|||.||||..:||::  |.|.
Frog   169 HLNAD-------LKSPSKYLRNKAVGEDAVREAFPDAIIMKPSEIYGREDRFFNHYANM--RWFG 224

  Fly   244 SMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVGPKRYQLSELVDWFHRLMRKDQK 308
            .:||...|:|:|||||||.|||:||:||..||:|.|:.|..|||.||.|.:||::...:..:.
Frog   225 GVPLIAFGKKSVKQPVYVVDVAKAILNAIHDPESKGKTYALVGPNRYLLHDLVEYIFAVTHRP-- 287

  Fly   309 RWGYMRYDMRWDPTFLLKAK---LNSFICPGTPIGGLHPARIEREAVTDKVLTGVPTLEDLGVTL 370
               ::.|.:. .|.:.|.::   :|.|. |.|.     ..:::|...|||....:|.|||||:..
Frog   288 ---FVPYPIP-RPLYRLISRFFEINPFE-PWTT-----RDKVDRFHTTDKKFPDLPGLEDLGIVP 342

  Fly   371 TTMEQQVPWELRPYRAALYYDAELGE 396
            |::||:....||.:|...:.:|:|.|
Frog   343 TSVEQKGIEVLRRHRRYRWLEADLDE 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-39	NP_001262116.1	NDUFA9_like_SDR_a	64..354	CDD:187579	129/292 (44%)
ND-39	NP_001262116.1	Epimerase	66..282	CDD:279681	111/215 (52%)
ndufa9	NP_001011432.1	NDUFA9_like_SDR_a	54..326	CDD:187579	129/292 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2632
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3666
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2951
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D465933at33208
OrthoFinder	1	1.000	-	-		FOG0004832
OrthoInspector	1	1.000	-	-		oto102665
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3413
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060